Patents by Inventor Laurent Billon

Laurent Billon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260201076
    Abstract: The present invention relates to a conjugate of a saccharide compound, selected from di-, oligo- and polysaccharides, and at least one hydrophobic compound selected from terpenes, polyterpenes and polyterpene ethers, where the hydrophobic compound in the conjugate is either directly bound to an oxygen atom of the saccharide or is present as a radical of the formulae (I) or (II): where in the formulae (I) and (II) R is a radical of a terpene compound, a polyterpene or a polyterpene ether compound k is 0 or 1, Y is C(O) or C(O)NH, A1 is a direct bond or C1-C6 alkylene, A2 is C2-C10 alkylene, X1 is C(O), or may also be OC(O) or NHC(O) if k=1 and A1 is C1-C6 alkylene and where X1 is attached to an oxygen atom of the saccharide compound, X2 is C(O)NH or NHC(O)NH, X3— is N? or NH—, and where X3 in formula (II) is attached to a carbon atom of the saccharide compound. The invention also relates to the use of such a conjugate as a stabilizer for an aqueous emulsion of a water-immiscible liquid.
    Type: Application
    Filed: November 27, 2023
    Publication date: July 16, 2026
    Inventors: Claude TARANTA, Pierre-Eric MILLARD, Laurent BILLON, Vinay CHAUHAN
  • Publication number: 20260165963
    Abstract: The present invention relates to a biodegradable microgel composition comprising an oligo (ethylene glycol)-based copolymers crosslinked with a modified chitosan cross-linker obtainable by reaction of a chitosan with monomers comprising —COOH or —COO-M+ groups, M? representing a cation, wherein said microgel composition comprises microgel particles. This microgel composition is able to form cohesive films spontaneously, which are biodegradable and feature mechano-electrical properties which are useful for the delivery of cosmetic or therapeutic agents of different nature.
    Type: Application
    Filed: October 25, 2023
    Publication date: June 18, 2026
    Inventors: Laurent BILLON, Garbine AGUIRRE UGARTE
  • Patent number: 12642839
    Abstract: Mucoadhesive microgel compositions, which include an active agent (such as HB-EGF), are provided. Aspects of the invention include a microgel comprising a crosslinked poly(ethylene glycol) methyl ether methacrylate polymer comprising a mucoadhesive functionality. Also provided are methods of making and using the mucoadhesive microgel compositions, e.g., in therapeutic applications. In one embodiment, HB-EGF loaded mucoadhesive microgel compositions are provided, e.g., for prevention or treatment of mucositis conditions, such as therapy induced oral mucositis conditions.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: June 2, 2026
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR, Centre National de la Recherche Scientifique
    Inventors: Laurent Billon, Eva Dieuzy, Garbine Aguirre, Solange Massa, Peter Luke Santa Maria
  • Publication number: 20240189249
    Abstract: The present invention relates to a composition comprising an oligo(ethylene glycol)-based polymers microgel crosslinked with a catechol cross-linker, said microgel comprises microgel particles, and wherein the microgel particles have a shell of conductive polymer. This composition is able to form cohesive films spontaneously with enhanced conductive and mechano-electrical properties.
    Type: Application
    Filed: March 24, 2022
    Publication date: June 13, 2024
    Inventors: Garbine AGUIRRE UGARTE, Pierre MARCASUZAA, Laurent BILLON
  • Publication number: 20230414461
    Abstract: The present invention deals with organic cosmetic active molecules encapsulation into temperature-responsive and pH-responsive oligo(ethylene glycol)-based biocompatible microgels that are incorporated into cosmetic compositions for controlled delivery on skin or hair.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Inventors: Valérie ALARD, Garbine AGUIRRE, Laurent BILLON
  • Publication number: 20230069954
    Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application, said composition comprising the combination of a crosslinked oligo(ethylene glycol) based polymer in the form of an aqueous dispersion of microgel particles and a non-crosslinked water-soluble oligo(ethylene glycol) polymer. The invention also relates to a process for preparing this composition.
    Type: Application
    Filed: November 27, 2020
    Publication date: March 9, 2023
    Inventors: Eva DIEUZY, Laurent BILLON, Christophe DERAIL, Valérie ALARD, Kamel CHOUGRANI
  • Publication number: 20230076159
    Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application, said composition comprising the combination of a crosslinked oligo(ethylene glycol) based polymer in the form of an aqueous dispersion of microgel particles and a non-crosslinked water-soluble oligo(ethylene glycol) polymer. The invention also relates to a process for preparing this composition.
    Type: Application
    Filed: November 27, 2020
    Publication date: March 9, 2023
    Inventors: Eva DIEUZY, Laurent BILLON, Christophe DERAIL, Valérie ALARD, Kamel CHOUGRANI
  • Publication number: 20220226436
    Abstract: Mucoadhesive microgel compositions, which include an active agent (such as HB-EGF), are provided. Aspects of the invention include a microgel comprising a crosslinked poly(ethylene glycol) methyl ether methacrylate polymer comprising a mucoadhesive functionality. Also provided are methods of making and using the mucoadhesive microgel compositions, e.g., in therapeutic applications. In one embodiment, HB-EGF loaded mucoadhesive microgel compositions are provided, e.g., for prevention or treatment of mucositis conditions, such as therapy induced oral mucositis conditions.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 21, 2022
    Inventors: Laurent BILLON, Eva DIEUZY, Garbine AGUIRRE, Solange MASSA, Peter Luke SANTA MARIA
  • Patent number: 11319428
    Abstract: Disclosed is a method for the use, as fire-retardant, of an aqueous composition including chitosan and at least one mineral filler, the inorganic filler being for example chosen from the group of mineral fillers in laminae, in particular chosen from the group consisting of talc, montmorillonite, saponite, sepiolite, bentonite, smectite, hectorite, kaolinite, halloysite and mica, and mixtures thereof.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: May 3, 2022
    Assignees: UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT TECHNOLOGIQUE FCBA
    Inventors: Gilles Labat, Céline Baguenard, Laurent Billon
  • Patent number: 11319390
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: May 3, 2022
    Assignees: LVMH RECHERCHE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PAU ET DES PAYS DE 1'ADOUR
    Inventors: Jean-Francois Tranchant, Emilie Gombart, Laurent Billon, Maud Save, Mohamed Boularas
  • Publication number: 20200377674
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Application
    Filed: July 13, 2020
    Publication date: December 3, 2020
    Inventors: Jean-Francois TRANCHANT, Emilie GOMBART, Laurent BILLON, Maud SAVE, Mohamed BOULARAS
  • Patent number: 10745527
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: August 18, 2020
    Assignees: LVMH RECHERCHE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR
    Inventors: Jean-Francois Tranchant, Emilie Gombart, Laurent Billon, Maud Save, Mohamed Boularas
  • Publication number: 20200197266
    Abstract: The present invention deals with organic cosmetic active molecules encapsulation into temperature-responsive and pH-responsive oligo(ethylene glycol)-based biocompatible microgels that are incorporated into cosmetic compositions for controlled delivery on skin or hair.
    Type: Application
    Filed: November 2, 2018
    Publication date: June 25, 2020
    Inventors: Valérie ALARD, Garbine AGUIRRE, Laurent BILLON
  • Publication number: 20200062932
    Abstract: Disclosed is a method for the use, as fire-retardant, of an aqueous composition including chitosan and at least one mineral filler, the inorganic filler being for example chosen from the group of mineral fillers in laminae, in particular chosen from the group consisting of talc, montmorillonite, saponite, sepiolite, bentonite, smectite, hectorite, kaolinite, halloysite and mica, and mixtures thereof.
    Type: Application
    Filed: November 3, 2017
    Publication date: February 27, 2020
    Inventors: Gilles LABAT, Céline BAGUENARD, Laurent BILLON
  • Publication number: 20190218349
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Application
    Filed: March 20, 2019
    Publication date: July 18, 2019
    Inventors: Jean-Francois TRANCHANT, Emilie GOMBART, Laurent BILLON, Maud SAVE, Mohamed BOULARAS
  • Patent number: 10287403
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: May 14, 2019
    Assignees: LVMH RECHERCHE, CENTRE NATIONAL DE LA RECHERCHE, UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR
    Inventors: Jean-Francois Tranchant, Emilie Gombart, Laurent Billon, Maud Save, Mohamed Boularas
  • Publication number: 20180002493
    Abstract: The invention relates to poly(oligo(ethylene glycol) methacrylate) microgels, to the process for preparing same and the uses thereof in various fields of application such as optics, electronics, pharmacy and cosmetics. These microgels have the advantage of being monodisperse, pH-responsive and temperature-responsive. They can carry magnetic nanoparticles or biologically active molecules. These microgels may also form transparent films, which have novel optical and electromechanical properties.
    Type: Application
    Filed: January 6, 2015
    Publication date: January 4, 2018
    Inventors: Jean-Francois TRANCHANT, Emilie GOMBART, Laurent BILLON, Maud SAVE, Mohamed BOULARAS
  • Publication number: 20070232748
    Abstract: The present invention describes a composite material based on a polymer matrix in which carbon nanotubes are dispersed, and also a process for obtaining such a material. The process of the invention is based on the use, as compatibilizer, of a block copolymer obtained by controlled radical polymerization and having at least one block bearing acid and/or anhydride functions. Such a compatibilizer makes it possible to control and optimize the interfacial interactions and thus to obtain a stable composite material that has good properties for use.
    Type: Application
    Filed: May 10, 2005
    Publication date: October 4, 2007
    Inventors: Olivier Guerret, Christelle Guerret-Piecourt, Laurent Billon, Vitaliy Datsyuk
  • Patent number: 6872781
    Abstract: A polymer blend is described which contains at least one acrylic resin or vinyl resin having at least one ionic or ionizable group and at least one thermoplastic fluoropolymer. Preferably, the polymer blend is an intimate blend of the two polymers which are useful in a variety of applications including in the formation of a membrane which is useful in batteries and fuel cells and the like. Methods of making the polymer blends are also described.
    Type: Grant
    Filed: September 24, 2003
    Date of Patent: March 29, 2005
    Assignee: Arkema Inc.
    Inventors: Lotfi Hedhli, Laurent Billon, Michel Foure, Ramin Amin-Sanayei
  • Patent number: 6780935
    Abstract: A polymer blend is described which contains at least one acrylic resin or vinyl resin having at least one ionic or ionizable group and at least one thermoplastic fluoropolymer. Preferably, the polymer blend is an intimate blend of the two polymers which are useful in a variety of applications including in the formation of a membrane which is useful in batteries and fuel cells and the like. Methods of making the polymer blends are also described.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: August 24, 2004
    Assignee: Atofina Chemicals, Inc.
    Inventors: Lotfi Hedhli, Laurent Billon