Patents by Inventor Laurent Blanchoin

Laurent Blanchoin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHOTO-MICROPATTERNING FOR ELECTRON MICROSCOPY
    Publication number: 20220301810
    Abstract: The invention relates to electron microscopy (EM) supports for in situ cryo-electron tomography, particularly to contactless and mask-free photo-micropatterning of EM grids for site-specific deposition of extracellular matrix-related proteins for micromachining by cryo-focused ion beam milling. The new EM supports allow for analysis of intracellular organization, permitting direct correlation of cell biology and biomechanics by 3D-structural characterization of the underlying molecular machinery in cellulo.
    Type: Application
    Filed: June 19, 2020
    Publication date: September 22, 2022
    Inventors: Julia MAHAMID, Mauricio TORO-NAHUELPAN, Laurent BLANCHOIN
  • Devices and methods for controlling actin filaments growth and organization using micropatterned nucleation sites
    Patent number: 9902757
    Abstract: The present invention concerns devices and methods for controlling actin filament growth and organization with micropatterned nucleation sites, and their uses for studying actin network formation, for screening of drugs or for preparing complex structures.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: February 27, 2018
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIER—GRENOBLE 1
    Inventors: Manuel Thery, Laurent Blanchoin, Rajaa Paterski
  • Method for obtaining three-dimensional actin structures and uses thereof
    Patent number: 9070702
    Abstract: The present invention relates to a method for preparing three-dimensional actin structures having a well-defined shape and displaying improved mechanical rigidity. This method comprises the steps of (a) providing a polymerization solution comprising actin monomers, a branching agent and a capping agent, (b) providing at least one surface having thereon a pattern which is coated with a nucleating agent, and (c) contacting the at least one surface of step (b) with the polymerization solution of step (a) so as to induce the polymerization of actin and obtain the said desired three-dimensional actin structure. Applications of the present invention in various technological fields such as microelectronics are also provided.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 30, 2015
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Christophe Gabriel, Laurent Blanchoin, Manuel Thery, Remi Galland
  • METHOD FOR OBTAINING THREE-DIMENSIONAL ACTIN STRUCTURES AND USES THEREOF
    Publication number: 20150048513
    Abstract: The present invention relates to a method for preparing three-dimensional actin structures having a well-defined shape and displaying improved mechanical rigidity. This method comprises the steps of (a) providing a polymerization solution comprising actin monomers, a branching agent and a capping agent, (b) providing at least one surface having thereon a pattern which is coated with a nucleating agent, and (c) contacting the at least one surface of step (b) with the polymerization solution of step (a) so as to induce the polymerization of actin and obtain the said desired three-dimensional actin structure. Applications of the present invention in various technological fields such as microelectronics are also provided.
    Type: Application
    Filed: February 7, 2013
    Publication date: February 19, 2015
    Inventors: Jean-Christophe Gabriel, Laurent Blanchoin, Manuel Thery, Remi Galland
  • DEVICES AND METHODS FOR CONTROLLING ACTIN FILAMENTS GROWTH AND ORGANIZATION USING MICROPATTERNED NUCLEATION SITES
    Publication number: 20130130394
    Abstract: The present invention concerns devices and methods for controlling actin filaments growth and organization with micro patterned nucleation sites, their uses for studying actin network formation, for screening of drugs or for preparing complex structures.
    Type: Application
    Filed: August 9, 2011
    Publication date: May 23, 2013
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE JOSEPH FOURIER- GRENOBLE 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Manuel Thery, Laurent Blanchoin, Rajaa Paterski