Patents by Inventor Laurent Bracco

Laurent Bracco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • P53 protein variants and therapeutic uses thereof
    Patent number: 6326464
    Abstract: Proteins derived from the product of tumor suppressor gene p53 and having enhanced functions for therapeutical use are disclosed. The proteins advantageously have enhanced tumour suppressor and programmed cell death inducer functions, particularly in proliferative disease contexts where wild-type p53 protein is inactivated. Nucleic acids coding for such molecules, vectors containing same, and therapeutical use thereof, particularly in gene therapy, are also disclosed.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: December 4, 2001
    Assignee: Aventis Pharma S.A.
    Inventors: Emmanuel Conseiller, Laurent Bracco
  • Differential Qualitative screening
    Patent number: 6251590
    Abstract: The present invention is directed to a method for identifying and/or cloning within a biological sample alternatively spliced nucleic acid regions ocurring between two physiological conditions, comprising hybridizing RNA derived from a test condition with cDNA derived from the standard condition and further identifying and/or cloning nucleic acids corresponding to alternative forms of splicing.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: June 26, 2001
    Assignee: ExonHit Therapeutics S.A.
    Inventors: Fabien Schweighoffer, Laurent Bracco, Bruno Tocque
  • Rapid test for determining the amount of functionally inactive gene in a gene therapy vector preparation
    Patent number: 5637456
    Abstract: The present invention relates generally to the area of quality control for recombinant agents to be used in gene therapy. Specifically, the invention concerns an assay used to identify the percentage of defective or therapeutically inactive vector in a vector stock.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: June 10, 1997
    Assignees: The University of Texas, Board of Regents, Rhone Poulenc Rorer
    Inventors: Jack A. Roth, Wei Wei Zhang, Bruno Tocque, Laurent Bracco