Patents by Inventor Laurent Chatel-Chaix

Laurent Chatel-Chaix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammalian staufen and use thereof
    Publication number: 20040241845
    Abstract: The present invention relates to mammalian Staufen, a double-stranded RNA-binding protein involved in mRNA transport and localization. The invention further relates to the demonstration of the association of a RNA-binding protein with the rough endoplasmic reticulum (RER), implicating Staufen and related proteins in the transport of RNA to its site of translation. Broadly, the invention therefore relates to transport and translation of RNA. More specifically, the present invention relates to human and mouse Staufen proteins and to the modulation of transport of RNA to the RER by these proteins. The present invention also relates to isolated nucleic acid molecules encoding mammalian Staufen, as well as vectors and host cells harboring same. In addition, the present invention relates to screening assays for identifying modulators of Staufen activity and to the identification of mutants thereof which abrogate their interaction with RER.
    Type: Application
    Filed: April 8, 2004
    Publication date: December 2, 2004
    Inventors: Luc Desgroseillers, Andrew Mouland, Laurent Chatel-Chaix, Jean-Francois Clement