Patents by Inventor Laurent Coen

Laurent Coen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10621601
    Abstract: A computer system for identifying utility cost savings is provided. The computer system includes a memory and at least one processor coupled to the memory. The at least one processor is configured to receive usage information gathered from at least one site via a first interface, administer a utility questionnaire via a second interface, and determine recommendation information describing a plurality of cost savings recommendations for the at least one site based on a set of responses to the questionnaire and the usage information.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: April 14, 2020
    Assignee: SCHNEIDER ELECTRIC USA, INC.
    Inventors: Laurent Coene, Edgard Franco
  • Publication number: 20140114724
    Abstract: A computer system for identifying utility cost savings is provided. The computer system includes a memory and at least one processor coupled to the memory. The at least one processor is configured to receive usage information gathered from at least one site via a first interface, administer a utility questionnaire via a second interface, and determine recommendation information describing a plurality of cost savings recommendations for the at least one site based on a set of responses to the questionnaire and the usage information.
    Type: Application
    Filed: April 26, 2012
    Publication date: April 24, 2014
    Applicant: SCHNEIDER ELECTRIC USA INC.
    Inventors: Laurent Coene, Edgard Franco
  • Publication number: 20110002914
    Abstract: The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the LacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and ?gal enzymatic activity. After intramuscular injection, enzymatic activity can be detected in motoneurons and connected neurons of brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells.
    Type: Application
    Filed: July 7, 2010
    Publication date: January 6, 2011
    Inventors: LAURENT COEN, ROSARIO OSTA PINZOLAS, PHILIPPE BRULET
  • Publication number: 20100239534
    Abstract: The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the IacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and ?-gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells.
    Type: Application
    Filed: June 26, 2008
    Publication date: September 23, 2010
    Inventors: Laurent Coen, Rosario Osta Pinzolas, Philippe Brulet
  • Publication number: 20090226468
    Abstract: The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the lacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and -gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells.
    Type: Application
    Filed: June 21, 2007
    Publication date: September 10, 2009
    Applicant: Institut Pasteur
    Inventors: Laurent Coen, Rosario Osta Pinzolas, Philippe Brulet
  • Patent number: 7435792
    Abstract: The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the IacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and ?-gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: October 14, 2008
    Assignee: Institut Pasteur
    Inventors: Laurent Coen, Rosario Osta Pinzolas, Philippe Brulet
  • Publication number: 20030004121
    Abstract: The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the IacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and &bgr;-gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells.
    Type: Application
    Filed: March 26, 2001
    Publication date: January 2, 2003
    Applicant: Institut Pasteur
    Inventors: Laurent Coen, Rosario Osta Pinzolas, Philippe Brulet