Abstract: Provided herein are methods of treating myositis using an effective amount of a human neonatal Fc receptor (FcRn) antagonist. FcRn antagonists for use in the treatment of myositis and for use in the manufacture of a medicament for the treatment of myositis are also provided herein.

Abstract: The invention relates to a method for opening a movable cover of the type that is movable along a predefined path, between a closed position and an open position, by motorized movement means that are activatable by at least one command, the cover comprising locking means designed to immobilize the cover in the closed position, the cover comprising obstruction detection means which are designed to detect obstructions that might be found on the predefined path, the method comprising a detection step (ET1), following a user actioning (AC) a command, which step comprises using the obstruction detection means to detect an obstruction that might be found on the path, the method further comprising a deactivation step (ET2) which comprises deactivating the locking means in order to allow the cover to move, the detection step (ET1) and the unlocking step (ET2) being initiated simultaneously

Abstract: Coronaviridae is a family of enveloped, positive-sense, single-stranded RNA viruses. The viral genome is 26-32 kilobases in length. In late December 2019, a new betacoronavirus SARS-CoV-2 has emerged in Wuhan China. The World Health Organization has named the severe pneumonia caused by this new coronavirus COVID-19 (for Corona Virus Disease 2019, WHO, 2020). To fight against the COVID-19 pandemic in a long term, in addition to the containment measures implemented in many countries, reliable diagnostic methods are highly desirable. In particular, the development and availability of tests for the detection and quantification of anti-SARS-CoV-2 antibodies in subjects with COVID-19 is of strong diagnostic interest. The present fulfils this need. In particular, the inventors developed an 15 Adressable Laser Beads ImmunoAssay (ALBIA) method based on the use of particles conjugated with a coronaviral polypeptides (S1,S2, S2?, N, PL-Pro).

Abstract: The present disclosure provides methods of treating inflammatory indications with complement inhibitor compounds and compositions. Included are compounds and methods of treating neuromuscular inflammatory indications, such as Immune-Mediated Necrotizing Myopathy.

Abstract: Method for producing a reinforcement beam for a vehicle, comprising at least one weak zone arranged in such a way that the bending resistance of the beam is less in said weak zone than in the rest of the beam, characterized in that it comprises, in order, a step (A) of extruding a profile part, a step (B) of cutting the profile part so as to obtain at least one profile segment, a step (C) of locally deforming the segment of the profile part in order to create the weak zone or zones.

Abstract: Method for producing a reinforcement beam for a vehicle, comprising at least one weak zone arranged in such a way that the bending resistance of the beam is less in said weak zone than in the rest of the beam, characterised in that it comprises, in order, a step (A) of extruding a profile part, a step (B) of cutting the profile part so as to obtain at least one profile segment, a step (C) of locally deforming the segment of the profile part in order to create the weak zone or zones.

Abstract: A mobile deflector device of a curved vehicle shield, comprising a central deflector and two lateral deflectors, essentially forming three chords distributed over the entire length of the shield. Each of the three deflectors is mounted such as to be able to pivot between a folded position and a second unfolded position substantially perpendicular to the first position.

Abstract: A mobile deflector device of a curved vehicle shield, comprising a central deflector and two lateral deflectors, essentially forming three chords distributed over the entire length of the shield. Each of the three deflectors is mounted such as to be able to pivot between a folded position and a second unfolded position substantially perpendicular to the first position.