Patents by Inventor Laurent Duc

Laurent Duc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme for the preparation of 1-amino-4-(hydroxymethyl)-2-cyclopentene derivatives
    Patent number: 7405065
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxy-methyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: July 29, 2008
    Assignee: Lonza AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Publication number: 20040265985
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae 1
    Type: Application
    Filed: July 21, 2004
    Publication date: December 30, 2004
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof and microorganisms useful in process
    Patent number: 6787347
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: September 7, 2004
    Assignee: LONZA AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Publication number: 20030008360
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae 1
    Type: Application
    Filed: November 14, 2001
    Publication date: January 9, 2003
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of amino alcohols and derivatives thereof
    Patent number: 6368850
    Abstract: The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol derivatives of the general formulae and to novel microorganisms which are able to utilize a cyclopentene derivative of the general formula as sole nitrogen source, as sole carbon source or as sole carbon and nitrogen source. The invention further relates to enzyme extracts and enzymes having N-acetylamino-alcohol hydrolase activity obtainable from these microorganisms.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: April 9, 2002
    Assignee: Lonza AG
    Inventors: Christine Bernegger-Egli, Olwen M. Birch, Pierre Bossard, Walter Brieden, Frank Brux, Knut Burgdorf, Laurent Duc, Kay-Sarah Etter, Yves Guggisberg, Martin Sauter, Eva Maria Urban
  • Process for the preparation of a racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivative
    Patent number: 6262295
    Abstract: A process for the preparation of a racemic or optically active compound of the formula where the group R1 is an unsubstituted or a halogen substituted C1-4-alkyl, a C1-4-alkoxy, an aryl, an arylalkyl, an aryloxy, or arylalkylloxy.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: July 17, 2001
    Assignee: Lonza A.G.
    Inventors: Christine Bernegger, Eva Maria Urban, Olwen Mary Birch, Kurt Burgdorf, Frank Brux, Kay-Sara Etter, Pierre Bossard, Walter Brieden, Laurent Duc, John Gordon, Colm O'Murchu, Yves Guggisberg
  • Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative
    Patent number: 6252112
    Abstract: A novel process for the preparation of (1S, 4R)- or (1R, 4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2 -cyclopentene-1-methanol of the formula is described.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: June 26, 2001
    Assignee: Lonza A.G.,
    Inventors: Christine Bernegger, Eva Maria Urban, Olwen Mary Birch, Kurt Burgdorf, Frank Brux, Kay-Sara Etter, Pierre Bossard, Walter Brieden, Laurent Duc, John Gordon, Colm O'Murchu, Yves Guggisberg
  • Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol
    Patent number: 6156893
    Abstract: A novel process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclo-pentene-1-methanol of the formulae ##STR1## is described. This entails in the first stage (.+-.)-2-aza-bicyclo[2.2.1]hept-5-en-3-one of the formula ##STR2## being acylated to give a (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one derivative of the general formula ##STR3## in which R.sup.1 denotes C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, aryl or aryloxy, the latter being reduced in the second stage to give a cyclopentene derivative of the general formula ##STR4## in which R.sup.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: December 5, 2000
    Assignee: Lonza A.G.
    Inventors: Christine Bernegger, Eva Maria Urban, Olwen Mary Birch, Kurt Burgdorf, Frank Brux, Kay-Sara Etter, Pierre Bossard, Walter Brieden, Laurent Duc, John Gordon, Colm O'Murchu, Yves Guggisberg
  • Enantiomer compositions of (1R,4S)-1-butyrylamino-4-(hydroxymethyl)-2-cyclopentene
    Patent number: 6137007
    Abstract: A novel process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol of the formulae ##STR1## is described. This entails in the first stage (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one of the formula ##STR2## being acylated to give a (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one derivative of the general formula ##STR3## in which R.sup.1 denotes C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, aryl or aryloxy, the latter being reduced in the second stage to give a cyclopentene derivative of the general formula ##STR4## in which R.sup.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: October 24, 2000
    Assignee: Lonza AG
    Inventors: Christine Bernegger, Eva Maria Urban, Olwen Mary Birch, Knut Burgdorf, Frank Brux, Kay-Sara Etter, Pierre Bossard, Walter Brieden, Laurent Duc, John Gordon, Colm O'Murchu, Yves Guggisberg
  • Process for the production of tetronic acid alkyl esters
    Patent number: 5144047
    Abstract: Tetronic acid alkyl esters are produced at a higher temperature by a ring closure of 4-halo-3-alkoxy-2-butene carboxylic acids. The tetronic acid alkyl esters are reacted by in acid hydrolysis in tetronic acid.
    Type: Grant
    Filed: July 19, 1990
    Date of Patent: September 1, 1992
    Assignee: Lonza Ltd.
    Inventors: Laurent Duc, John McGarrity
  • Process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters
    Patent number: 4966989
    Abstract: A process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters starting from 4-chloroacetoacetic acid chloride by reaction with a dialkyl sulfite. The produced intermediate products are used as structural elements for, i.a., pharmaceutical agents.
    Type: Grant
    Filed: June 8, 1989
    Date of Patent: October 30, 1990
    Assignee: Lonza Ltd.
    Inventor: Laurent Duc
  • 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters
    Patent number: 4880940
    Abstract: 4-Alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters are intermediate products for the production of cerebrally-active pharmaceutical products. The advantageous process for production of the new intermediate products is described.
    Type: Grant
    Filed: July 22, 1988
    Date of Patent: November 14, 1989
    Assignee: Lonza Ltd.
    Inventors: Thomas Muel, Leander Tenud, Laurent Duc, John McGarrity
  • Process for the production of 4-alkoxy-3-pyrrolin-2-ones
    Patent number: 4788294
    Abstract: Process for the production of 4-alkoxy-3-pyrrolin-2-ones, which are preferred intermediate products for the production of cerebrally-active pharmaceutical products.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: November 29, 1988
    Assignee: Lonza Ltd.
    Inventors: Laurent Duc, John McGarrity, Thomas Meul
  • Production of 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters
    Patent number: 4780545
    Abstract: 4-Alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters are intermediate products for the production of cerebrally-active pharmaceutical products. The advantageous process for production of the new intermediate products is described.
    Type: Grant
    Filed: November 18, 1986
    Date of Patent: October 25, 1988
    Assignee: Lonza Ltd.
    Inventors: Thomas Meul, Leander Tenud, Laurent Duc, John McGarrity