Patents by Inventor Laurent Gutmann

Laurent Gutmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE SCREENING OF ANTIBACTERIAL SUBSTANCES
    Publication number: 20150094229
    Abstract: The present invention concerns a method for the screening of antibacterial substances comprising a step of determining the ability of a candidate substance to inhibit the activity of a purified enzyme selected from the group consisting of: (i) a D-aspartate ligase comprising a polypeptide having an amino acid sequence possessing at least 50% amino acid identity with an amino acid sequence selected from the group consisting of SEQ ID No 1 to SEQ ID No 10, or a biologically active fragment thereof; and (ii) a L,D-transpeptidase comprising a polypeptide having an amino acid sequence possessing at least 50% amino acid identity with the amino acid sequence of SEQ ID No 11, or a biologically active fragment thereof.
    Type: Application
    Filed: October 7, 2014
    Publication date: April 2, 2015
    Inventors: Jean-Luc MAINARDI, Laurent GUTMANN, Michel ARTHUR, Samuel BALLAIS, Jean Emmanuel HUGONNET, Claudine MAYER, Sabrina BIAROTTE-SORIN
  • Methods for treating latent tuberculosis
    Patent number: 8258127
    Abstract: A method for treating individuals affected with latent tuberculosis comprising a step of administering an effective amount of one or more carbapenem compounds to the said individuals.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: September 4, 2012
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Jean-Luc Mainardi, Michel Arthur, Laurent Gutmann, Marie Lavollay
  • METHODS FOR TREATING LATENT TUBERCULOSIS
    Publication number: 20100022504
    Abstract: A method for treating individuals affected with latent tuberculosis comprising a step of administering an effective amount of one or more carbapenem compounds to the said individuals.
    Type: Application
    Filed: July 28, 2008
    Publication date: January 28, 2010
    Applicant: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: JEAN-LUC MAINARDI, MICHEL ARTHUR, LAURENT GUTMANN, MARIE LAVOLLAY
  • Methods for the Screening of Antibacterial Substances
    Publication number: 20090311714
    Abstract: The present invention concerns a method for the screening of antibacterial substances comprising a step of determining the ability of a candidate substance to inhibit the activity of a purified enzyme selected from the group consisting of: (i) a D-aspartate ligase comprising a polypeptide having an amino acid sequence possessing at least 50% amino acid identity with an amino acid sequence selected from the group consisting of SEQ ID No 1 to SEQ ID No 10, or a biologically active fragment thereof; and (ii) a L,D-transpeptidase comprising a polypeptide having an amino acid sequence possessing at least 50% amino acid identity with the amino acid sequence of SEQ ID No 11, or a biologically active fragment thereof.
    Type: Application
    Filed: August 1, 2006
    Publication date: December 17, 2009
    Applicants: UNIVERSITE RENE DESCARTES, INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Jean-Luc Mainardi, Laurent Gutmann, Michel Arthur, Samuel Bellais, Jean Emmanuel Hugonnet, Claudine Mayer, Sabrina Biarotte-Sorin