Patents by Inventor Laurent HOFFER

Laurent HOFFER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEOXYCYTIDINE KINASE INHIBITORS
    Publication number: 20250092032
    Abstract: The present invention relates to compounds of formula (I) as deoxycytidine kinase inhibitors and pharmaceutical compositions comprising the same. The present invention further relates to the use of such compounds of formula (I) for use for treating a cancer.
    Type: Application
    Filed: January 17, 2023
    Publication date: March 20, 2025
    Inventors: SÉBASTIEN ABEL, STÉPHANE BETZI, KHAOULA BEN YAALA-BEN MOUSSA, PAUL BREMOND, SÉBASTIEN COMBES, PATRICE DUBREUIL, LAURENT HOFFER, XAVIER MORELLI, ETIENNE REBUFFET, PHILIPPE ROCHE, MAGALI SAEZ-AYALA, BENOIT SICARD
  • Xanthine derivatives and uses thereof as inhibitors of bromodomains of BET proteins
    Patent number: 11180510
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)—or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: November 23, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Stéphane Betzi, Sébastien Combes, Yves Collette, Laurent Hoffer, Xavier Morelli, Brigit Raux, Philippe Roche, Iuliia Voitovich
  • XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS
    Publication number: 20200377522
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)— or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers
    Type: Application
    Filed: November 6, 2018
    Publication date: December 3, 2020
    Inventors: Stéphane BETZI, Sébastien COMBES, Yves COLLETTE, Laurent HOFFER, Xavier MORELLI, Brigit RAUX, Philippe ROCHE, Iuliia VOITOVICH