Abstract: Multispecific proteins that bind and specifically redirect NK cells to lyse a target cell of interest are provided without non-specific activation of NK cells in absence of target cells. The proteins have utility in the treatment of disease, notably cancer or infections disease.

Abstract: A method of transmitting data between an electronic transmitter device and an electronic receiver device connected together by a data link, the method comprising the steps of: sending the data in the form of at least three identical frames sent in succession and each associated with respective checkdata calculated on the frame in question; and the electronic receiver device verifying the validity of the received frames as they are being received and making the first valid frame available for processing while ignoring the others.

Abstract: A method of transmitting data between an electronic transmitter device and an electronic receiver device connected together by a data link, the method comprising the steps of: sending the data in the form of at least three identical frames sent in succession and each associated with respective checkdata calculated on the frame in question; and the electronic receiver device verifying the validity of the received frames as they are being received and making the first valid frame available for processing while ignoring the others.

Abstract: The present invention relates to a method of controlling the operation of a processing device in a first mode or in a second mode. The processing device has a first execution environment and a second execution environment. The method comprises, upon detection of a switch between said first and second modes, setting in the first execution environment a value of a shared variable to an initial value, upon detection of a request of execution of instructions in the second execution environment, updating the value of said shared variable to a value different from the initial value, and reading a current value of the shared variable and causing the processing device to operate in the first mode or in the second mode depending at least on the current value of the shared variable.

Abstract: The present invention relates to a method of controlling the operation of a processing device in a first mode or in a second mode. The processing device has a first execution environment and a second execution environment. The method comprises, upon detection of a switch between said first and second modes, setting in the first execution environment a value of a shared variable to an initial value, upon detection of a request of execution of instructions in the second execution environment, updating the value of said shared variable to a value different from the initial value, and reading a current value of the shared variable and causing the processing device to operate in the first mode or in the second mode depending at least on the current value of the shared variable.

Abstract: A method for manufacturing a field sensor including a series of n probes, in which n>=3, each formed of a core of magnetic alloys associated with a coil. According to the invention, the method includes the steps of ensuring the deposit of cores of magnetic alloys onto a non-magnetic substrate, on at least part or the entirety of a surface corresponding to a series of n strips extending along axes (x, y, z) concurrent at an intersection and connected by an intersection region (z), before or after this deposit, cutting out the n strips in the substrate leaving them connected to the substrate by at least one attachment, assembling each strip with a coil, and folding at least one strip along a fold line perpendicular to the axis thereof.

Abstract: A push-actuated control device for watches includes a push-piece button (1) connected with a push-piece shaft (2) passing through a push-piece pipe (3) intended to be accommodated in the watchcase. The device further includes a compression ring (4) screwed onto the push-piece pipe (3) and a compression gasket (5) placed between pipe (3) and ring (4), the gasket (5) being compressed while ring (4) is in a screwed first position. Compression ring (4) on a segment of its inner circumference includes a twofold axial stop (4.1, 4.2), and push-piece button (1) includes a projection (1.1) on its outer circumference, so that compression ring (4) cooperates with push-piece button (1) to block the push-piece button (1) in its first position, and liberate it in an unscrewed second position.

Abstract: A push-actuated control device for watches includes a push-piece button (1) connected with a push-piece shaft (2) passing through a push-piece pipe (3) intended to be accommodated in the watchcase. The device further includes a compression ring (4) screwed onto the push-piece pipe (3) and a compression gasket (5) placed between pipe (3) and ring (4), the gasket (5) being compressed while ring (4) is in a screwed first position. Compression ring (4) on a segment of its inner circumference includes a twofold axial stop (4.1, 4.2), and push-piece button (1) includes a projection (1.1) on its outer circumference, so that compression ring (4) cooperates with push-piece button (1) to block the push-piece button (1) in its first position, and liberate it in an unscrewed second position.

Abstract: A damping device, more particularly for a watchcase, includes a case (1) the back (7) of which has an extension provided with a groove (13) holding a gasket (14). The device further includes a support (2, 3) the lower segment (2) of which has a compression chamber (18) cooperating with the extension of the back of case (1), this extension being able to move axially, and in air-tight fashion, in this chamber (18). This lower segment (2) of the support is linked to a ring (3) against which case (1) leans in its rest position.

Abstract: A damping device, more particularly for a watchcase, includes a case (1) the back (7) of which has an extension provided with a groove (13) holding a gasket (14). The device further includes a support (2, 3) the lower segment (2) of which has a compression chamber (18) cooperating with the extension of the back of case (1), this extension being able to move axially, and in air-tight fashion, in this chamber (18). This lower segment (2) of the support is linked to a ring (3) against which case (1) leans in its rest position.

Abstract: A device includes a supporting tube fixed at the case of a watch, a drive shaft with teeth extending inside the supporting tube for controlling at least one function of the watch, a crown having a crown's head and a tube with teeth integral with the crown's head that is mounted so as to be mobile in rotation and translation, between the inner wall of the supporting tube and the drive shaft, and an indexing gasket seated in the inner wall of the supporting tube and cooperating with first and second grooves provided on the outside of the mobile tube in order to define a first axial position of the crown in which the mobile tube is engaged with the drive shaft and can transmit a torque to it, and a second axial position of the crown in which the mobile tube is disengaged from the drive shaft.

Abstract: A device includes a supporting tube fixed at the case of a watch, a drive shaft with teeth extending inside the supporting tube for controlling at least one function of the watch, a crown having a crown's head and a tube with teeth integral with the crown's head that is mounted so as to be mobile in rotation and translation, between the inner wall of the supporting tube and the drive shaft, and an indexing gasket seated in the inner wall of the supporting tube and cooperating with first and second grooves provided on the outside of the mobile tube in order to define a first axial position of the crown in which the mobile tube is engaged with the drive shaft and can transmit a torque to it, and a second axial position of the crown in which the mobile tube is disengaged from the drive shaft.