Patents by Inventor Laurent Naudin

Laurent Naudin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses
    Patent number: 7378274
    Abstract: The present invention concerns a nucleic acid which is capable of regulating the transcription of the ABC1 gene, which is a causal gene for pathologies linked to a dysfunctioning of cholesterol metabolism, inducing diseases such as atherosclerosis. The invention also relates to nucleotide constructs comprising a polynucleotide which encodes a polypeptide or a nucleic acid of interest, placed under the control a regulatory nucleic acid for the ABC1 gene. The invention also relates to recombinant vectors, transformed host cells and nonhuman transgenic mammals comprising a nucleic acid which regulates the transcription of the ABC1 gene or an abovementioned nucleotide construct, as well as methods for screening molecules or substances which are capable of modifying the activity of the regulatory nucleic acid for the ABC1 gene.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: May 27, 2008
    Assignee: Aventis Pharma S.A.
    Inventors: Marie-Françoise Rosier-Montus, Catherine Prades, Cendrine Lemoine, Laurent Naudin, Patrice Denefle, Nicolas Duverger, Bryan Brewer, Alan Remaley, Sylvia Santamarina-Fojo
  • Nucleic and proteinic acids corresponding to human gene ABC1
    Publication number: 20040185456
    Abstract: The invention relates to nucleic acids corresponding to different exons and introns of gene ABC1 which is shown to be a gene causing pathologies linked to cholesterol metabolism dysfunction causing diseases such as atherosclerosis, more particularly perturbation of reverse cholesterol transport and more particularly the FHD's such as Tangier Disease
    Type: Application
    Filed: June 18, 2003
    Publication date: September 23, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Patrice Denefle, Marie-Francoise Rosier-Montus, Isabelle Arnould-Reguigne, Catherine Prades, Laurent Naudin, Cendrine Lemoine, Nicolas Duverger, Stephan Rust, Gerd Assmann, Harald Funke, H. Bryan Brewer
  • Nucleic acids of the human ABCA12 gene, vectors containing such nucleic acids and uses thereof
    Publication number: 20030087246
    Abstract: The present invention relates to a novel human ABCA12 gene as well as cDNAs encoding the novel full and short length ABCA12 proteins. The invention also relates to vectors and recombinants host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCA12 gene or in the corresponding protein produced by the allelic form of the ABCA12 gene.
    Type: Application
    Filed: February 12, 2002
    Publication date: May 8, 2003
    Inventors: Isabelle Arnould-Reguigne, Catherine Prades, Laurent Naudin, Cendrine Lemoine, Michael Dean, Patrice Denefle, Marie-Francoise Rosier-Montus
  • Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses
    Publication number: 20020146792
    Abstract: The present invention concerns a nucleic acid which is capable of regulating the transcription of the ABC1 gene, which is a causal gene for pathologies linked to a dysfunctioning of cholesterol metabolism, inducing diseases such as atherosclerosis.
    Type: Application
    Filed: May 2, 2001
    Publication date: October 10, 2002
    Inventors: Marie-Francoise Rosier-Montus, Catherine Prades, Cendrine Lemoine, Laurent Naudin, Patrice Denefle, Nicolas Duverger, Bryan Brewer, Alan Remaley, Sylvia Santamarina-Fojo
  • Method for preparing a recombinant adenovirus genome
    Patent number: 6261807
    Abstract: A novel method for preparing recombinant adenoviruses and the use of such adenoviruses in gene therapy are disclosed. Plasmids used in the construction of said adenoviruses are also disclosed.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: July 17, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Joël Crouzet, Laurent Naudin, Patrice Yeh, Cécile Orsini, Emmanuelle Vigne