Patents by Inventor Laurent Poulain

Laurent Poulain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Computer-implemented process on an image of a biological sample
    Patent number: 11756194
    Abstract: Computer-implemented process on an image of a biological sample The present invention relates to a computer-implemented process to automatically analyze a digital image (103) of abiological sample (101). The process involves a change (203) from a first color space to a second color space. Then, fits are performed taking into account several dimensions of the second color space to classify pixels.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: September 12, 2023
    Assignees: Vilniaus Universitetas;, Universite De Caen Normandie, Institut National De La Sante Et De La Recherche Medicale, Centre Regional Francois Baclesse
    Inventors: Laurent Poulain, Arvydas Laurinavicius, Benoît Plancoulaine, Nicolas Elie
  • PREDICTIVE AND PROGNOSTIC USE OF A miRNA FOR HIGH GRADE SEROUS OVARIAN CARCINOMA THERAPEUTIC CARE
    Publication number: 20210269883
    Abstract: The present disclosure relates to the identification of a biomarker, consisting in a circulating miRNA, suitable for use in the diagnosis and prognosis of high-grade serous ovarian carcinoma (HGSOC), and to diagnostic kits for use in such diagnosis.
    Type: Application
    Filed: July 4, 2019
    Publication date: September 2, 2021
    Applicants: UNIVERSITE DE CAEN NORMANDIE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE REGIONAL FRANCOIS BACLESSE, UNIVERSITE GRENOBLE ALPES
    Inventors: Nicolas VIGNERON, Christophe DENOYELLE, Laurent POULAIN, Jean-Paul ISSARTEL, Bernard LAMBERT, Matthieu MERYET-FIGUIERE, Mégane VERNON, Audrey GUTTIN
  • COMPUTER-IMPLEMENTED PROCESS ON AN IMAGE OF A BIOLOGICAL SAMPLE
    Publication number: 20210272280
    Abstract: Computer-implemented process on an image of a biological sample The present invention relates to a computer-implemented process to automatically analyze a digital image (103) of abiological sample (101). The process involves a change (203) from a first color space to a second color space. Then, fits are performed taking into account several dimensions of the second color space to classify pixels.
    Type: Application
    Filed: June 27, 2019
    Publication date: September 2, 2021
    Inventors: Laurent POULAIN, Arvydas LAURINAVICIUS, Benoît PLANCOULAINE, Nicolas ELIE
  • Mcl-1 modulating compounds for cancer treatment
    Patent number: 10307410
    Abstract: The invention relates to compounds of formula (I), and to their therapeutic use in the treatment of cancer: Wherein Y1, Y2, Ar1, Ar2, R1, R2, i, j, k, l are as defined in claim 1.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: June 4, 2019
    Assignees: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER FRANCOIS BACLESSE, UNIVERSITE DE CAEN BASSE-NORMANDIE, INSTITUT DE CANCEROLOGIE DE L'OUEST RENE GAUDUCHEAU
    Inventors: Laurent Poulain, Anne-Sophie Voisin-Chiret, Jana Sopkova-de Oliveira Santos, Ronan Bureau, Grégory Burzicki, Marcella De Giorgi, Serge Perato, Jade Fogha, Sylvain Rault, Philippe Juin, Fabien Gautier
  • MCL-1 MODULATING COMPOUNDS FOR CANCER TREATMENT
    Publication number: 20170071921
    Abstract: The invention relates to compounds of formula (I), and to their therapeutic use in the treatment of cancer: Wherein Y1, Y2, Ar1, Ar2, R1, R2, i, j, k, l are as defined in claim 1.
    Type: Application
    Filed: March 3, 2015
    Publication date: March 16, 2017
    Applicants: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER FRANCOIS BACLESSE, UNIVERSITE DE CAEN BASSE-NORMANDIE, INSTITUT DE CANCEROLOGIE DE L'OUEST RENE GAUDUCHEAU
    Inventors: Laurent POULAIN, Anne-Sophie VOISIN-CHIRET, Jana SOPKOVA-DE OLIVEIRA SANTOS, Ronan BUREAU, Grégory BURZICKI, Marcella DE GIORGI, Serge PERATO, Jade FOGHA, Sylvain RAULT, Philippe JUIN, Fabien GAUTIER
  • CANCER THERAPY USING Bcl-XL-SPECIFIC siNA
    Publication number: 20130237584
    Abstract: The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.
    Type: Application
    Filed: May 15, 2012
    Publication date: September 12, 2013
    Applicant: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER - CENTRE FRANCOIS BACLESSE
    Inventors: Laurent Poulain, Pascal Gauduchon, Emilie Brotin, Ester Saison-Behmoaras
  • Cancer therapy using Bcl-X-specific siNA
    Patent number: 8193333
    Abstract: The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: June 5, 2012
    Assignee: Centre Regional de Lutte Contre le Cancer-Centre Francois Baclesse
    Inventors: Laurent Poulain, Pascal Gauduchon, Emilie Brotin, Ester Saison-Behmoaras
  • CANCER THERAPY USING BCL-XL-SPECIFIC SINA
    Publication number: 20090312393
    Abstract: The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.
    Type: Application
    Filed: June 22, 2007
    Publication date: December 17, 2009
    Applicant: CENTRE REGIONAL DE LUTTE CONTRE LE CANCER - CENTRE FRANCOIS BACLESSE
    Inventors: Laurent Poulain, Pascal Gauduchon, Emilie Brotin, Ester Saison-Behmoaras