Patents by Inventor Laurent TANGUY
Laurent TANGUY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11471850Abstract: The present application concerns a microfluidic cassette for synthesizing a radiotracer including a microfluidic circuit in a support card that includes at least one intake for supply by a vial, at least one isotope port, at least one reaction chamber, at least one mixing chamber, at least one formulation chamber, and at least one connection for a syringe, linked together by capillaries. Also disclosed is a method for synthesizing a radiotracer in such a cassette.Type: GrantFiled: October 12, 2018Date of Patent: October 18, 2022Assignee: P M BInventors: Virginie Hourtane, Laurent Tanguy, Florian Pineda
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Patent number: 11219875Abstract: Disclosed is a device for the synthesis of a radiotracer, including a universal confined enclosure designed for the insertion of a specific synthesis cassette of the radiotracer and the removal of same. The synthesis cassette includes a synthesis module designed to receive reagents and a radioisotope for the synthesis of the radiotracer. An inner connector plate includes at least one inlet, designed to be connected to a radioisotope admission and also to the inlet of the cassette, and an outlet, designed to be connected to a syringe to be filled with the radiotracer and also to the outlet of the cassette. Such a synthesis device can be installed in a facility including, in a confined room, as well as such devices normally arranged in a storage area, a synthesis station, a radioisotope admission, at least one window for communication to the outside, and a manipulator robot.Type: GrantFiled: April 14, 2016Date of Patent: January 11, 2022Assignee: PMBInventors: Laurent Tanguy, Jerome Corneille, Bertrand Loubaton, Marc Delmas, Alain Perez Delaume
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Publication number: 20200238249Abstract: The present application concerns a microfluidic cassette for synthesizing a radiotracer including a microfluidic circuit in a support card that includes at least one intake for supply by a vial, at least one isotope port, at least one reaction chamber, at least one mixing chamber, at least one formulation chamber, and at least one connection for a syringe, linked together by capillaries. Also disclosed is a method for synthesizing a radiotracer in such a cassette.Type: ApplicationFiled: October 12, 2018Publication date: July 30, 2020Inventors: Virginie HOURTANE, Laurent TANGUY, Florian PINEDA
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Patent number: 10466264Abstract: A dispensing assembly comprising a cartridge holder is presented. The cartridge holder can receive a cartridge for dispensing a fluid. The cartridge can comprise a reservoir for receiving the fluid. The reservoir can comprise an outlet. The reservoir can have an adjustable volume for forcing the fluid through the outlet. The cartridge can further comprise a nozzle for dispensing the fluid. The nozzle can be connected to the outlet. The dispensing assembly can further comprise an actuator for actuating the adjustable volume. The dispensing assembly can further comprise an impulse generator for imparting an impulse to the nozzle. The impulse generator can comprise an actor for contacting the nozzle. The dispenser assembly can further comprise a controller for controlling the actor and the impulse generator.Type: GrantFiled: November 3, 2014Date of Patent: November 5, 2019Assignee: Roche Diagnostics Operations, Inc.Inventors: Stefan Borja Bammesberger, Andreas Ernst, Peter Koltay, Nadine Losleben, Laurent Tanguy
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Patent number: 10252273Abstract: A valve for dispensing a fluid comprising a dry portion and a wet portion is presented. Only the wet portion is contacted by the fluid. The wet portion comprises a fluid dispenser unit having a inlet opening, a capillary nozzle providing a fluid outlet, a cavity, the capillary nozzle having an end within the cavity, and a plunger. The plunger moves within the cavity into an opening position allowing an inflow of the fluid through the inlet opening through the cavity and an outflow of the fluid through the capillary nozzle. The plunger has a sealing surface directed towards the end of the capillary nozzle. The plunger moves into a closing position for sealing the end of the capillary nozzle with the sealing surface. The dry portion comprises a closing component for exercising a magnetic closing force onto the plunger for attracting the plunger into the closing position.Type: GrantFiled: November 3, 2014Date of Patent: April 9, 2019Assignee: Roche Diagnostics Operations, Inc.Inventors: Stefan Borja Bammesberger, Sabrina Kartmann, Peter Koltay, Klaus Mutschler, Juergen Spinke, Laurent Tanguy
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Publication number: 20180071704Abstract: Disclosed is a device for the synthesis of a radiotracer, including a universal confined enclosure designed for the insertion of a specific synthesis cassette of the radiotracer and the removal of same. The synthesis cassette includes a synthesis module designed to receive reagents and a radioisotope for the synthesis of the radiotracer. An inner connector plate includes at least one inlet, designed to be connected to a radioisotope admission and also to the inlet of the cassette, and an outlet, designed to be connected to a syringe to be filled with the radiotracer and also to the outlet of the cassette. Such a synthesis device can be installed in a facility including, in a confined room, as well as such devices normally arranged in a storage area, a synthesis station, a radioisotope admission, at least one window for communication to the outside, and a manipulator robot.Type: ApplicationFiled: April 14, 2016Publication date: March 15, 2018Inventors: Laurent TANGUY, Jerome CORNEILLE, Bertrand LOUBATON, Marc DELMAS, Alain PEREZ DELAUME
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Patent number: 9573131Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.Type: GrantFiled: November 3, 2014Date of Patent: February 21, 2017Assignee: Roche Diagnostics Operations, Inc.Inventors: Thorsten Brueckner, Peter Koltay, Norbert Oranth, Juergen Spinke, Laurent Tanguy
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Patent number: 9459128Abstract: A device for dispensing or receiving a liquid volume includes a liquid reservoir having an outlet, a pressure generator which provides a compressible enclosed gas volume of a constant amount of substance with a pressure, wherein the gas volume is in direct or indirect fluidic contact with the liquid in the liquid reservoir, a dosing device coupled to the outlet of the liquid reservoir and operable in order to enable the liquid to pass the outlet, a pressure sensor arranged to measure a current pressure in the gas volume and to output an output signal indicating the current pressure in the gas volume and a controller coupled to the pressure generator, the dosing device and the pressure sensor.Type: GrantFiled: May 31, 2013Date of Patent: October 4, 2016Assignees: Hahn-Schickard-Gesellschaft fuer angewandte Forschung e.V., Albert-Ludwigs-Universitaet FreiburgInventors: Peter Koltay, Andreas Ernst, Chris Steinert, Laurent Tanguy
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Publication number: 20150224500Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid and for receiving a ventilation gas. The reservoir chamber comprises an inlet for receiving the ventilation gas and an outlet for dispensing the fluid. At least a portion of the reservoir chamber is filled with the ventilation gas when in an operating position. The inlet is located in the portion being filled with the ventilation gas. The fluid comprises a reagent. The cartridge further comprises a baffle for restricting gas diffusion through the inlet. The reservoir chamber receives the ventilation gas via the baffle. The inlet is maintains a constant gas pressure within the portion of the reservoir chamber that is being filled with the ventilation gas.Type: ApplicationFiled: November 3, 2014Publication date: August 13, 2015Inventors: Thorsten Brueckner, Peter Koltay, Norbert Oranth, Juergen Spinke, Laurent Tanguy
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Publication number: 20150050719Abstract: A dispensing assembly comprising a cartridge holder is presented. The cartridge holder can receive a cartridge for dispensing a fluid. The cartridge can comprise a reservoir for receiving the fluid. The reservoir can comprise an outlet. The reservoir can have an adjustable volume for forcing the fluid through the outlet. The cartridge can further comprise a nozzle for dispensing the fluid. The nozzle can be connected to the outlet. The dispensing assembly can further comprise an actuator for actuating the adjustable volume. The dispensing assembly can further comprise an impulse generator for imparting an impulse to the nozzle. The impulse generator can comprise an actor for contacting the nozzle. The dispenser assembly can further comprise a controller for controlling the actor and the impulse generator.Type: ApplicationFiled: November 3, 2014Publication date: February 19, 2015Inventors: Stefan Borja Bammesberger, Andreas Ernst, Peter Koltay, Nadine Losleben, Laurent Tanguy
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Publication number: 20150050186Abstract: A valve for dispensing a fluid comprising a dry portion and a wet portion is presented. Only the wet portion is contacted by the fluid. The wet portion comprises a fluid dispenser unit having a inlet opening, a capillary nozzle providing a fluid outlet, a cavity, the capillary nozzle having an end within the cavity, and a plunger. The plunger moves within the cavity into an opening position allowing an inflow of the fluid through the inlet opening through the cavity and an outflow of the fluid through the capillary nozzle. The plunger has a sealing surface directed towards the end of the capillary nozzle. The plunger moves into a closing position for sealing the end of the capillary nozzle with the sealing surface. The dry portion comprises a closing component for exercising a magnetic closing force onto the plunger for attracting the plunger into the closing position.Type: ApplicationFiled: November 3, 2014Publication date: February 19, 2015Inventors: Stefan Borja Bammesberger, Sabrina Kartmann, Peter Koltay, Klaus Mutschler, Juergen Spinke, Laurent Tanguy
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Publication number: 20130327787Abstract: A device for dispensing or receiving a liquid volume comprises a liquid reservoir having an outlet, a pressure generation means which is implemented to provide a compressible enclosed gas volume of a constant amount of substance with a pressure, wherein the gas volume is in direct or indirect fluidic contact with the liquid in the liquid reservoir, a dosing means coupled to the outlet of the liquid reservoir and operable in order to enable the liquid to pass the outlet, a pressure sensor for measuring a current pressure in the gas volume and for outputting an output signal indicating the current pressure in the gas volume and a controller coupled to the pressure generation means, the dosing means and the pressure sensor.Type: ApplicationFiled: May 31, 2013Publication date: December 12, 2013Inventors: Peter KOLTAY, Andreas ERNST, Chris STEINERT, Laurent TANGUY