Abstract: An arrangement for a hydraulically operated tool holder has a pressurizing system for operating a clamping device for a tool or workpiece. The pressurizing system comprises a movable operating element for pressure generation whereby the movement of the operating element causes a movement of a guideway which has an inclined or end or bend surface with respect to its direction of movement. The guideway coacts with the actuator rolling or sliding at the surface thereof whereby the movement resulting from the movement of the guideway is transmitted to at least one pressure transfer piston in a pressure cylinder. The pressure transfer piston comprises at least one support part for the actuator and a lip seal and coacts with the clamping device.