Patents by Inventor Laurie Brewer

Laurie Brewer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 186 Human Secreted Proteins
    Publication number: 20120122762
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 26, 2012
    Publication date: May 17, 2012
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, D. Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • ANTIBODIES TO HT5GJ57
    Publication number: 20110003383
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: November 10, 2008
    Publication date: January 6, 2011
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George A. Komatsoulis, D. Roxanne Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik S. Olsen, Laurie A. Brewer, Kimberly A Florence, Paul E. Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • 50 Human Secreted Proteins
    Publication number: 20090253626
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 1, 2008
    Publication date: October 8, 2009
    Inventors: Paul A. Moore, Steven M. Ruben, David W. LaFleur, Yanggu Shi, Craig A. Rosen, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer
  • 50 Human Secreted Proteins
    Publication number: 20090247482
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: November 21, 2008
    Publication date: October 1, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul A. Moore, Steven M. Ruben, David W. LaFleur, Yanggu Shi, Craig A. Rosen, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer
  • 186 Human Secreted Proteins
    Publication number: 20090011983
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: May 8, 2007
    Publication date: January 8, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, D. Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • 207 Human Secreted Proteins
    Publication number: 20090005301
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 7, 2007
    Publication date: January 1, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Reinhard Ebner, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Yanggu Shi, Kimberly A. Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie L. Fischer, Ann M. Ferrie, Ping Fan, Ping Feng, Gregory A. Endress, Patrick J. Dillon, Kenneth C. Carter, Laurie A. Brewer, Guo-Liang Yu, Zhizhen Zeng, John M. Greene
  • 50 Human secreted proteins
    Patent number: 7459531
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: December 2, 2008
    Assignee: Human Genome Sciences, Inc.
    Inventors: Paul A. Moore, Steven M. Ruben, David W. LaFleur, Yanggu Shi, Craig A. Rosen, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer
  • 98 Human Secreted Proteins
    Publication number: 20080051338
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 12, 2007
    Publication date: February 28, 2008
    Applicant: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig Rosen, Steven Ruben, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Ying-Fei Wei, Jian Ni, Kimberly Florence, Paul Young, Laurie Brewer, Daniel Soppet, Gregory Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • 36 Human Secreted Proteins
    Publication number: 20080020969
    Abstract: The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 24, 2008
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Daniel Soppet, Henrik Olsen, Steven Ruben, Jian Ni, Craig Rosen, Laurie Brewer, Roxanne Duan, Reinhard Ebner
  • 70 Human Secreted Proteins
    Publication number: 20070238664
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: May 22, 2007
    Publication date: October 11, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Craig Rosen, Carrie Fischer, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Yanggu Shi
  • Novel Metalloproteinases
    Publication number: 20070238130
    Abstract: The present invention relates to novel metalloproteinase- like proteins. In particular, isolated nucleic acid molecules are provided encoding the human TACE-like and matrilysin-like proteins. TACE-like and matrilysin-like polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TACE-like and matrilysin-like activity. Also provided are diagnostic methods for detecting cancer and therapeutic methods for cancer and other disorders characterized by an over or under production of these metalloproteinases.
    Type: Application
    Filed: January 25, 2007
    Publication date: October 11, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven Ruben, Laurie Brewer, Reiner Gentz, Craig Rosen
  • ANTIBODIES TO HHPEN62 POLYPEPTIDE
    Publication number: 20070172830
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: May 21, 2004
    Publication date: July 26, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Kimberly Florence, Jian Ni, Craig Rosen, Kenneth Carter, Paul Moore, Henrik Olsen, Yanggu Shi, Paul Young, Ying-Fei Wei, Laurie Brewer, Daniel Soppet, David LaFleur, Gregory Endress, Reinhard Ebner, Charles Birse
  • Antibodies to HHPEN62 polypeptide
    Patent number: 7247442
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: July 24, 2007
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Kimberly A. Florence, Jian Ni, Craig A. Rosen, Kenneth C. Carter, Paul A. Moore, Henrik S. Olsen, Yanggu Shi, Paul E. Young, Ying-Fei Wei, Laurie A. Brewer, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, Charles E. Birse
  • 87 Human Secreted Proteins
    Publication number: 20070154912
    Abstract: The present invention relates to 87 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 4, 2006
    Publication date: July 5, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Young, John Greene, Ann Ferrie, Steven Ruben, Craig Rosen, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Paul Moore, Yanggu Shi, David LaFleur, Jian Ni
  • 50 Human Secreted Proteins
    Publication number: 20070154910
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further re lates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 1, 2006
    Publication date: July 5, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Moore, Steven Ruben, David LaFleur, Yanggu Shi, Craig Rosen, Henrik Olsen, Reinhard Ebner, Laurie Brewer
  • Metalloproteinases
    Patent number: 7169566
    Abstract: The present invention relates to novel metalloproteinase-like proteins. In particular, isolated nucleic acid molecules are provided encoding the human TACE-like and matrilysin-like proteins. TACE-like and matrilysin-like polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TACE-like and matrilysin-like activity. Also provided are diagnostic methods for detecting cancer and therapeutic methods for cancer and other disorders characterized by an over or under production of these metalloproteinases.
    Type: Grant
    Filed: November 2, 2004
    Date of Patent: January 30, 2007
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, Laurie A. Brewer, Reiner L. Gentz, Craig A. Rosen
  • 94 human secreted proteins
    Publication number: 20070020724
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 9, 2004
    Publication date: January 25, 2007
    Inventors: Steven Ruben, Jian Ni, Craig Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel Soppet, Laurie Brewer, Gregory Endress, Kenneth Carter, Michael Mucenski, Reinhard Ebner, David LaFleur, Henrik Olsen, Yanggu Shi, Paul Moore, George Komatsoulis
  • 71 human secreted proteins
    Publication number: 20070014787
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 15, 2006
    Publication date: January 18, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, George Komatsoulis, D. Duan, Craig Rosen, Paul Moore, Yanggu Shi, David LaFleur, Reinhard Ebner, Henrik Olsen, Laurie Brewer, Kimberly Florence, Paul Young, Michael Mucenski, Gregory Endress, Daniel Soppet
  • 207 human secreted proteins
    Publication number: 20060223077
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 20, 2005
    Publication date: October 5, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Reinhard Ebner, David LaFleur, Paul Moore, Henrik Olsen, Craig Rosen, Steven Ruben, Daniel Soppet, Paul Young, Yanggu Shi, Kimberly Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie Fischer, Ann Ferrie, Ping Fan, Ping Feng, Gregory Endress, Patrick Dillon, Kenneth Carter, Laurie Brewer, Guo-Liang Yu, Zhizhen Zeng, John Greene
  • 90 human secreted proteins
    Publication number: 20060160126
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 15, 2006
    Publication date: July 20, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Daniel Soppet, Reinhard Ebner, Henrik Olsen, Paul Young, John Greene, Ann Ferrie, Guo-Liang Yu, Jian Ni, Craig Rosen, Laurie Brewer, Fouad Janat, Charles Birse