Patents by Inventor Laurie J. Hartman

Laurie J. Hartman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Internal positive control for probe-based nucleic acid molecule assays and methods of making and using thereof
    Patent number: 7052848
    Abstract: Disclosed herein are isolated nucleic acid molecules that may be used as an internal positive controls in probe-based nucleic acid assays such as TaqMan® based assays. Also disclosed are probes comprising the isolated nucleic acid molecule of the present invention. The probes may comprise a reporter molecule and a quencher molecule. Also disclosed are assays which comprise using the probe of the present invention. The probes may be used to distinguish false negative results from true negative results in assays for a target nucleic acid molecule. The probe may be used in conjunction with probe-based nucleic acid assays for the detection of an organism such as one belonging to Bacillus, Mycobacterium, Francisella, Brucella, Clostridium, Yersinia, Variola, Orthopox, or Burkholderia.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: May 30, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Laurie J. Hartman, David A. Norwood, Jr., Leonard P. Wasieloski, Jr.
  • Internal positive control for probe-based nucleic acid molecule assays and methods of making and using thereof
    Patent number: 7005267
    Abstract: Disclosed herein are isolated nucleic acid molecules that may be used as an internal positive controls in probe-based nucleic acid assays such as TaqMan® based assays. Also disclosed are probes comprising the isolated nucleic acid molecule of the present invention. The probes may comprise a reporter molecule and a quencher molecule. Also disclosed are assays which comprise using the probe of the present invention. The probes may be used to distinguish false negative results from true negative results in assays for a target nucleic acid molecule. The probe may be used in conjunction with probe-based nucleic acid assays for the detection of an organism such as one belonging to Bacillus, Mycobacterium, Francisella, Brucella, Clostridium, Yersinia, Variola, Orthopox, or Burkholderia.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: February 28, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Laurie J. Hartman, David A. Norwood, Jr.
  • Internal positive control for probe-based nucleic acid molecule assays and methods of making and using thereof
    Publication number: 20030211527
    Abstract: Disclosed herein are isolated nucleic acid molecules that may be used as an internal positive controls in probe-based nucleic acid assays such as TaqMan® based assays. Also disclosed are probes comprising the isolated nucleic acid molecule of the present invention. The probes may comprise a reporter molecule and a quencher molecule. Also disclosed are assays which comprise using the probe of the present invention. The probes may be used to distinguish false negative results from true negative results in assays for a target nucleic acid molecule. The probe may be used in conjunction with probe-based nucleic acid assays for the detection of an organism such as one belonging to Bacillus, Mycobacterium, Francisella, Brucella, Clostridium, Yersinia, Variola, Orthopox, or Burkholderia.
    Type: Application
    Filed: March 3, 2003
    Publication date: November 13, 2003
    Inventors: Laurie J. Hartman, David A. Norwood