Patents by Inventor Laurie J. Ozelius

Laurie J. Ozelius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Torsin, torsin-related genes and methods of detecting neuronal disease
    Patent number: 6921814
    Abstract: The present invention relates to methods of detecting mutations and polymorphisms in the torsin gene, torsin-related genes, methods of detecting neuronal diseases mediated by these mutations and polymorphisms and nucleic acids used in these methods.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: July 26, 2005
    Assignee: The General Hospital Corporation
    Inventors: Laurie J. Ozelius, Xandra O. Breakefield
  • Torsin, torsin genes, and methods of use
    Patent number: 6387616
    Abstract: The present invention relates, in general, to dystonia. In particular, the present invention relates to nucleic acid molecules coding for the torsin protein; purified torsin proteins and polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to torsin proteins and polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of nucleic acids encoding torsin proteins; a method of detecting nucleic acids encoding torsin proteins and polypeptides in a sample; kits containing nucleic acid probes or antibodies; bioassays using the nucleic acid sequence, proteins or antibodies of this invention to diagnose the presence or absence of a dystonia; to assess, or prognose a human afflicted with torsion dystonia; therapeutic uses; and methods of preventing torsion dystonia in a human.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: May 14, 2002
    Assignee: The General Hospital Corporation
    Inventors: Laurie J. Ozelius, Xandra O. Breakefield
  • Torsin, torsin-related genes and methods of detecting neuronal disease
    Publication number: 20010029015
    Abstract: The present invention relates to methods of detecting mutations and polymorphisms in the torsin gene, torsin-related genes, methods of detecting neuronal diseases mediated by these mutations and polymorphisms and nucleic acids used in these methods.
    Type: Application
    Filed: January 26, 2001
    Publication date: October 11, 2001
    Applicant: The General Hospital Corporation
    Inventors: Laurie J. Ozelius, Xandra O. Breakefield