Patents by Inventor Laurie L. Voci
Laurie L. Voci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Apparatus and method for fluorescence imaging and tomography using spatially structured illumination
Patent number: 9801548Abstract: Apparatus and method for performing depth sectioned fluorescence imaging of a turbid sample including a fluorescent turbid medium, uses an apparatus for quantitative modulated fluorescence imaging, the apparatus including projection optics with a first optical axis, to expose the turbid sample to a periodic pattern of excitation radiation to provide depth-resolved discrimination of fluorescent structures within the turbid medium; an image capture module, including a second optical axis and a detection beam path, to receive a data image from the sample; and a signal processor to transform the data image from the sample, spatially filter the transformed data image from the sample, and reconstruct the filtered, transformed data image from the sample.Type: GrantFiled: August 5, 2013Date of Patent: October 31, 2017Assignee: Bruker Biospin CorporationInventors: Gilbert Feke, Laurie L. Voci -
APPARATUS AND METHOD FOR FLUORESCENCE IMAGING AND TOMOGRAPHY USING SPATIALLY STRUCTURED ILLUMINATION
Publication number: 20140088438Abstract: An imaging system for imaging an object. More specifically, an imaging system enabling depth sectioned fluorescence imaging in a turbid medium, such as human or animal tissue, to substantially minimize the excitation radiation from reaching the detection beam path. The imaging system includes an arrangement of the excitation radiation source wherein the optical axis of the source is inclined relative to the optical axis of the camera, the optical plane of the source and the optical plane of the object are subject to a Scheimpflug condition, and the angle of inclination of the source is selected such that the excitation radiation incident upon the object is reflected to minimize excitation radiation from reaching the detection beam path.Type: ApplicationFiled: August 5, 2013Publication date: March 27, 2014Applicant: Bruker Biospin CorporationInventors: Gilbert Feke, Laurie L. Voci -
Apparatus and method for fluorescence imaging and tomography using spatially structured illumination
Patent number: 8504140Abstract: An imaging system for imaging an object. More specifically, an imaging system enabling depth sectioned fluorescence imaging in a turbid medium, such as human or animal tissue, to substantially minimize the excitation radiation from reaching the detection beam path. The imaging system includes an arrangement of the excitation radiation source wherein the optical axis of the source is inclined relative to the optical axis of the camera, the optical plane of the source and the optical plane of the object are subject to a Scheimpflug condition, and the angle of inclination of the source is selected such that the excitation radiation incident upon the object is reflected to minimize excitation radiation from reaching the detection beam path.Type: GrantFiled: March 26, 2009Date of Patent: August 6, 2013Assignee: Bruker BioSpin CorporationInventors: Gilbert Feke, Laurie L. Voci -
Patent number: 7994485Abstract: An apparatus and method for depth selected fluorescence measurements is provided. The apparatus may include a carrier for at least one sample substance; projection optics; an image capture module; a signal processor to transform the data image to provide depth selected fluorescence measurement for the at least one sample substance. The apparatus is arranged such that a first optical axis is inclined relative to a second optical axis so that the projection optics have an angle of inclination relative to the image plane. The angle of inclination is selected so that a component of excitation radiation incident upon, but not absorbed by, the at least one sample substance is scattered or reflected to reduce excitation radiation from reaching the detection beam path.Type: GrantFiled: September 10, 2009Date of Patent: August 9, 2011Assignee: Carestream Health, Inc.Inventors: Gilbert Feke, Laurie L. Voci
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Publication number: 20100038559Abstract: An apparatus is disclosed for depth selected fluorescence measurements of a sample.Type: ApplicationFiled: September 10, 2009Publication date: February 18, 2010Inventors: Gilbert Feke, Laurie L. Voci
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APPARATUS AND METHOD FOR FLUORESCENCE IMAGING AND TOMOGRAPHY USING SPATIALLY STRUCTURED ILLUMINATION
Publication number: 20090250631Abstract: An imaging system is disclosed for imaging an object. More specifically, an improvement is disclosed in an imaging system enabling depth sectioned fluorescence imaging in a turbid medium, such as human or animal tissue, in such a manner as to substantially minimize the excitation radiation from reaching the detection beam path. The imaging system includes an arrangement of the excitation radiation source such that the optical axis of the source is inclined relative to the optical axis of the camera, the optical plane of the source and the optical plane of the object are subject to a Scheimpflug condition provided by projection optics, and the angle of inclination of the source is selected such that the excitation radiation incident upon the object is reflected in such a way that substantially minimizes excitation radiation from reaching the detection beam path.Type: ApplicationFiled: March 26, 2009Publication date: October 8, 2009Inventors: Gilbert Feke, Laurie L. Voci -
Publication number: 20080118886Abstract: An apparatus (10) for obtaining an image of a tooth (20) includes an image sensor and a white light source (12) providing broadband polychromatic light and an ultraviolet light source providing narrow-band light. A combiner (15) directs broadband polychromatic light and narrow band light along a common illumination path to illuminate the tooth. A polarization beamsplitter (18) directs polarized light from the illumination path along an optical axis (216). An optical coherence tomography (OCT) imaging apparatus (70) splits the low coherence light into a sample path and a reference path and a dichroic element (78) directs the polarized illumination and the sample path low coherence light along the optical axis. An image processor (100) identifies a region of interest according to either a white light image (124), a fluorescent light image (120), or both and the OCT imaging apparatus obtains an OCT image over the region of interest.Type: ApplicationFiled: November 21, 2006Publication date: May 22, 2008Inventors: Rongguang Liang, Michael A. Marcus, David L. Patton, Laurie L. Voci, Victor C. Wong, Paul O. McLaughlin, Mark E. Bridges
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Patent number: 5936652Abstract: According to one aspect of the present invention, there is provided a printhead protective cover (50) which includes a shutter blade (60), an actuator (70) for moving the shutter blade (60), and a light trap (54) to prevent light from the printhead (12) from passing around the shutter blade (60). In one embodiment, a sensor detects a position of the shutter blade (60) and sends a signal to shutoff the actuator (70) when the shutter blade (60) is in an open position, or the shutter blade (60) is in a closed position. In yet another embodiment, the actuator (70) closes the shutter blade (60) in response to a tear in a web or failure of a dryer. In a further embodiment, the shutter blade (60) slides on a base plate coated with a low friction, non-volatile, non-liquid material, and the shutter blade (60) slides at an oblique angle on the base plate.Type: GrantFiled: July 31, 1997Date of Patent: August 10, 1999Assignee: Eastman Kodak CompanyInventors: Badhri Narayan, Robert C. Bryant, David J. Nelson, Laurie L. Voci
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Patent number: 5768674Abstract: An apparatus for creating copy restrictive media is disclosed comprising a linear array (20) comprised of at least two spatially distributed light sources (22) and an aperture mask (28) for forming two or more micro-light sources from the light sources (22). An optical element (32) focuses light from the micro-light sources onto a media (40) moving relative to the linear array (20). An encoder (16) turns the light sources (22) on and off at regular intervals relating to movement of the media (40).Type: GrantFiled: April 30, 1997Date of Patent: June 16, 1998Assignee: Eastman Kodak CompanyInventors: John Gasper, Badhri Narayan, Laurie L. Voci
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Patent number: 5162929Abstract: A three-color laser scanner using a holographically-generated plane linear grating disk (hologon). The disk includes peripherally-arranged facets having identical multiplexed diffraction gratings. Each multiplexed grating is formed from plural superimposed interference patterns accumulated by multiple exposures to light from a single monochromatic laser beam source. The multiplexed grating is optimized to diffract certain light wavelengths in a single, multichromatic (plural wavelength) input laser beam. The diffracted output beam comprises respective wavelength beam components that simultaneously scan in collinear fashion. Modulation of the plural wavelength components in the incident beam allows the output beam to scan expose a multicolor image at the image plane.Type: GrantFiled: July 5, 1991Date of Patent: November 10, 1992Assignee: Eastman Kodak CompanyInventors: James E. Roddy, Badhri Narayan, Robert H. Cuffney, Kevin J. Klees, Laurie L. Voci
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Patent number: 5026133Abstract: A large format laser scanning system is disclosed that incorporates a compact, wobble free and wavelength insensitive scanning mechanism. The scanning mechanism includes a pentaprism and lens mounted on a rotating frame assembly that is located within a scanning drum. Multiple light beams generated by a light source are passed through the rotating pentaprism and lens to scan a photosensitive medium located on the interior surface of the scanning drum.Type: GrantFiled: May 1, 1990Date of Patent: June 25, 1991Assignee: Torii Winding Machine Co., Ltd.Inventors: James E. Roddy, Badhri Narayan, Richard A. Stark, Laurie L. Voci
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Patent number: 4938596Abstract: A phase conjugate interferometer has a partially reflective conventional mirror placed in front of and in close proximity to a phase conjugate mirror using internally self pumped phase conjugation in barium titanate or other photorefractive material. The reflective surface may be the surface of the phase conjugate mirror. An optical system under test is illuminated with coherent light and the wavefront at the exit pupil thereof is imaged through a beam splitter onto the reflective surface (imaging being unnecessary if the distance between the exit pupil and the reflective surface is sufficiently small that negligible diffraction occurs over that distance). Part of the wavefront is reflected at the reflective surface of the partially reflecting conventional mirror. The transmitted portion of the wavefront is incident on the phase conjugate mirror where a wavefront reversed replica of the incident wave is produced and reflected.Type: GrantFiled: January 5, 1989Date of Patent: July 3, 1990Assignee: The University of RochesterInventors: Daniel J. Gauthier, Robert W. Boyd, Robert Jungquist, Laurie L. Voci