Patents by Inventor Lavakumar Karyampudi

Lavakumar Karyampudi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expansion Of Peripheral Blood Lymphocytes (PBLS) From Peripheral Blood
    Publication number: 20230340412
    Abstract: Methods of expanding tumor infiltrating lymphocytes (TILs), including peripheral blood lymphocytes (PBLs) and marrow infiltrating lymphocytes (MILs), from blood and/or bone marrow of patients with hematological malignancies, such as liquid tumors, including lymphomas and leukemias, and genetic modifications of expanded TILs, PBLs, and MILs to incorporate chimeric antigen receptors, genetically modified T-cell receptors, and other genetic modifications, and uses of such expanded and/or modified TILs, PBLs, and MILs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: March 13, 2023
    Publication date: October 26, 2023
    Inventors: Lavakumar Karyampudi, Maria Fardis
  • EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES FROM LIQUID TUMORS AND THERAPEUTIC USES THEROF
    Publication number: 20230165898
    Abstract: Methods of expanding peripheral blood lymphocytes (PBLs) from blood of patients with hematological malignancies, including lymphomas and leukemias, genetic modifications of expanded PBLs to incorporate chimeric antigen receptors, genetically modified T cell receptors, and other genetic modifications, and uses of such expanded and/or modified PBLs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: July 12, 2022
    Publication date: June 1, 2023
    Inventor: Lavakumar Karyampudi
  • EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES FROM LIQUID TUMORS AND THERAPEUTIC USES THEREOF
    Publication number: 20230092130
    Abstract: Methods of expanding tumor infiltrating lymphocytes (TILs), including peripheral blood lymphocytes and marrow infiltrating lymphocytes, from blood and/or bone marrow of patients with hematological malignancies, such as liquid tumors, including lymphomas and leukemias, and uses of such expanded TILs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: July 12, 2022
    Publication date: March 23, 2023
    Inventors: Lavakumar Karyampudi, Maria Fardis
  • METHODS AND COMPOSITIONS FOR SELECTING TUMOR INFILTRATING LYMPHOCYTES AND USES OF THE SAME IN IMMUNOTHERAPY
    Publication number: 20220249559
    Abstract: The present invention provides improved methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for selecting TILs responsive to a mutant polypeptide expressed by cancer cells and not expressed in normal tissue.
    Type: Application
    Filed: May 12, 2020
    Publication date: August 11, 2022
    Inventors: Seth Wardell, Maritza Lienlaf Moreno, Cecile Chartier-Courtaud, Lavakumar Karyampudi
  • Expansion of Tumor Infiltrating Lymphocytes From Liquid Tumors and Therapeutic Uses Thereof
    Publication number: 20220133795
    Abstract: Methods of expanding peripheral blood lymphocytes (PBLs) from blood of patients with hematological malignancies, including lymphomas and leukemias, genetic modifications of expanded PBLs to incorporate chimeric antigen receptors, genetically modified T cell receptors, and other genetic modifications, and uses of such expanded and/or modified PBLs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 5, 2022
    Inventor: Lavakumar Karyampudi
  • Expansion Of Peripheral Blood Lymphocytes (PBLS) From Peripheral Blood
    Publication number: 20200347350
    Abstract: Methods of expanding tumor infiltrating lymphocytes (TILs), including peripheral blood lymphocytes (PBLs) and marrow infiltrating lymphocytes (MILs), from blood and/or bone marrow of patients with hematological malignancies, such as liquid tumors, including lymphomas and leukemias, and genetic modifications of expanded TILs, PBLs, and MILs to incorporate chimeric antigen receptors, genetically modified T-cell receptors, and other genetic modifications, and uses of such expanded and/or modified TILs, PBLs, and MILs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: November 9, 2018
    Publication date: November 5, 2020
    Inventors: Lavakumar Karyampudi, Maria Fardis
  • EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES FROM LIQUID TUMORS AND THERAPEUTIC USES THEREOF
    Publication number: 20200224161
    Abstract: Methods of expanding tumor infiltrating lymphocytes (TILs), including peripheral blood lymphocytes and marrow infiltrating lymphocytes, from blood and/or bone marrow of patients with hematological malignancies, such as liquid tumors, including lymphomas and leukemias, and uses of such expanded TILs in the treatment of diseases such as cancers and hematological malignancies are disclosed herein.
    Type: Application
    Filed: May 10, 2018
    Publication date: July 16, 2020
    Inventors: Lavakumar Karyampudi, Maria Fardis