Patents by Inventor Lavanya Peddada

Lavanya Peddada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING WITH FIRBRONECTIN TYPE III LIKE DOMAIN MOLECULES
    Publication number: 20190184028
    Abstract: A fibronectin type III (FN3) domain-nanoparticle or direct conjugate complex containing a polynucleotide molecule, a toxin, polynucleotide molecule or other pharmaceutically active payload is obtained by panning an FN3 domain library with a protein or nucleotide of interest, recovering the FN3 domain and conjugating the FN3 domain with a toxin or nanoparticle containing an active polynucleotide, such as an ASO or siRNA molecule. A fibronectin type III (FN3) domain-nucleic acid conjugate is obtained by panning an FN3 domain library with a protein or nucleotide of interest, recovering the FN3 domain and conjugating the FN3 domain to a nucleic acid (e.g., ASO or siRNA). The nanoparticle complex, nucleic acid conjugate or FN3 domain toxin conjugate may be used in the treatment of diseases and conditions, for example, oncology or auto-immune indications.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 20, 2019
    Inventors: Vadim Dudkin, Andrew Elias, Shalom Goldberg, Donna Klein, Elise Kuhar, Tricia Lin, Lavanya Peddada, Karyn O'Neil, Kristen Wiley