Abstract: A composition comprising direct, indirect and related pathway endocannabinoid mimetic compounds and methods of using the composition.

Abstract: Skin hydration is necessary to maintain the epidermal barrier, minimize adverse environmental influences, and reduce cell stress. Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically and cosmetically acceptable salts thereof, and compositions, methods, and uses that may be used for skin hydration. Also reported herein is a scalable method for synthesizing compounds of Formula (I). The compounds provided herein are responsible for improved skin penetration and/or retention and are therefore useful for the treatment and/or prevention of various diseases, disorders, or conditions to protect human skin.

Abstract: A hair moisturizing topical composition comprising materials that emit electromagnetic radiation at wavelengths that affect tertiary structure (breaking of disulfide bonds) in human hair, and that bring about changes in secondary structure of hair proteins. The intensity of the radiation is controlled and sufficient to cause or facilitate altering of protein structure. The invention includes methods of using such topical compositions. Testing indicates that the level of tightly bound water in hair is increased, and there is no damage to hair of the type characteristic of heat and chemical treatments.

Abstract: The invention relates to a method of retaining, enhancing or imparting curl in a keratinous material which comprises applying to the keratinous material a retention effective amount of a transglutaminase enzyme.

Abstract: A cosmetic composition for reducing the appearance of lines, wrinkles and the size of pores in the skin is provided. The composition comprises a silica component, a silicon resin-coated elastomeric core component, and a cosmetic patch component, comprising algin/serine/atelocollagen, in a cosmetically acceptable aqueous vehicle.