Abstract: Compositions for antimicrobial, antibacterial, antiviral, fungicidal and sporicidal applications comprise a mixture of alkyl betaine and alkyl amine oxide components together with a protonating agent. The compositions are particularly effective in the treatment and elimination of microorganisms in planktonic cell form as well as in sessile cell form in biofilms. The compositions may be applied in the form of sprays and foams as well as in liquid forms, as a solution or as a balm, as the sole active ingredient or with other active ingredients together with carriers or diluents.

Abstract: A reservoir system for delivering an active agent into an oral cavity over an extended delivery period includes a pair of rigid plastic containers, which each have a hollow interior space for containing the active agent and at least one opening for dispensing the active agent, and a flexible plastic appliance for securing the containers within the oral cavity at a desired location. The containers are located within chambers formed in opposite sides of the appliance. The container includes a molded plastic body having a size and shape suitable for comfortably retaining the container within the oral cavity for the extended delivery time. The body is generally oval and cabochon-shaped to comfortably fit in the vestibule between the teeth/gums and cheek of the patient and has a plurality of dimples for selectively forming venting and dispensing holes at desired locations. The appliance is custom molded to closely fit the patient.

Abstract: A reservoir system for delivering an active agent into an oral cavity over an extended delivery period includes a pair of containers, which each have a hollow interior space for containing the active agent and at least one opening for dispensing the active agent, and a flexible plastic appliance for securing the containers within the oral cavity at a desired location. The containers are located within chambers formed in opposite sides of the appliance. The container includes a molded plastic body having a size and shape suitable for comfortably retaining the container within the oral cavity for the extended delivery time. The body is generally oval and cabochon-shaped to comfortably fit in the vestibule between the teeth/gums and cheek of the patient. The appliance is custom molded to closely fit the patient. The reservoir system can further include a foraminous medium for directly holding and dispensing an active agent at a desired treatment location within the oral cavity.