Abstract: Disclosed herein are positive allosteric modulators of melanocortin receptor and methods of using such modulators.

Abstract: Disclosed herein are positive allosteric modulators of melanocortin receptor and methods of using such modulators.

Abstract: A machine and method for anticipatory sensing and intervention to avoid swimmer entrapment, entanglement or evisceration; with a proactive, pre-entrapment, ultrasonic sensor assessing the relative hazard of swimmer proximity to a drain cover. A transducer launches waves into the suction piping and/or drain system, and receives echoes from the drain cover, swimmer limbs, hair or body, and water or wall surface parallel to the drain cover. A transmitter electrically energizes the transducer launching waves into the suction piping and/or drain system. A receiver/processor detects the echoes analog signals from the drain cover and water beyond the pool drain. A Logic and Control element converts the detected signals into reliable information regarding safety/hazard status for a swimmer near a drain. Predetermined logic provides automatic pump shutdown, and alarms as required; including a missing drain cover. A pool alarm mode detects that an object, such as a small child, has fallen in.

Abstract: A machine for anticipatory sensing and intervention to avoid swimmer entrapment, with an active pre-entrapment sensor (e.g. ultrasonic) that assesses the relative hazard based on swimmer proximity to the drain cover. An Ultrasonic Transducer launches waves into the suction piping and/or drain system, and receives echoes from the drain cover, swimmer limbs, hair or body, and the water surface parallel to the drain cover. A Transmitter/Pulser electrically energizes the ultrasonic transducer to launch waves into the suction piping and/or drain system, A Receiver/Processor detects the echoes electrical signals from the ultrasonic transducer. and receives echoes from objects of interest beyond the pool drain. A Logic and Control element converts the detected signals into reliable information regarding a swimmer safety/hazard status. An Output provides a pump shutdown command when required. There is also a pool alarm mode to detect, and a panic alert, that a child has fallen in.

Abstract: Modular Pool Safety Controller used with swimming pool or spa. The controller stands alone, or integrated with a prior art controller. Emphasis is on safety of swimmers and pool equipment, providing low entry cost. Other modular features can be added. Safety features; Swimmer Protection: Excess Suction triggers latched pump shut-down and suction dump valve that admits air into the pump inlet, instantly releasing suction entrapment. When reduced daylight combines with swimmer activity, Pool Lights are turned on. Remote Control provides Emergency shut-down. Equipment Protection: Low pump Pressure triggers latched pump shut-down. Remote Control initiates draining high water levels. Portable Intelligent Remote Alarms (PIRA) offer specific voice messages when pump shut-down occurs; guidance concerning cause and actions required, plus chimes and red lights. After Startup PIRA delivers a green OK light and specific voice message confirming the communications link.

Abstract: Modular Pool Safety Controller used with swimming pool or spa. The controller stands alone, or integrated with a prior art controller. Emphasis is on safety of swimmers and pool equipment, providing low entry cost. Other modular features can be added. Safety features; Swimmer Protection: Excess Suction triggers latched pump shut-down and suction dump valve that admits air into the pump inlet, instantly releasing suction entrapment. When reduced daylight combines with swimmer activity, Pool Lights are turned on. Remote Control provides Emergency shut-down. Equipment Protection: Low pump Pressure triggers latched pump shut-down. Remote Control initiates draining high water levels. Portable Intelligent Remote Alarms (PIRA) offer specific voice messages when pump shut-down occurs; guidance concerning cause and actions required, plus chimes and red lights. After Startup PIRA delivers a green OK light and specific voice message confirming the communications link.

Abstract: The present invention is to a touch sensitive intelligent multimodal peripheral device which includes a touch sensitive pad to which the operator applies a light pressure in a prescribed manner to effect cursor movement on a CRT screen or to input data to a computer. The device has four operating modes which are defined as the mouse mode, the absolute mode, the joystick mode and the numeric keypad mode.