Patents by Inventor Lawrence Alan Reiter

Lawrence Alan Reiter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indoles and methods of use thereof
    Patent number: 12116358
    Abstract: Compounds of Formula I: (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1e, G1, G2, Q1, Q2, Q3, and (II) are defined as set forth in the specification, as are uses of compounds of Formula I to treat a disease, disorder, or condition such as cancer in a subject.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: October 15, 2024
    Assignee: Epizyme, Inc.
    Inventors: John Lampe, John Campbell, Kenneth Duncan, Megan Alene Cloonan Foley, Darren Martin Harvey, Michael John Munchhof, Michael Thomenius, Lawrence Alan Reiter
  • SUBSTITUTED INDOLES AND METHODS OF USE THEREOF
    Publication number: 20230075198
    Abstract: The present disclosure provides substituted indole compounds of Formula I: (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1e, G1, G2, Q1, Q2, Q3, and (II) are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disease, disorder, or condition such as cancer in a subject.
    Type: Application
    Filed: August 14, 2019
    Publication date: March 9, 2023
    Inventors: John LAMPE, John CAMPBELL, Kenneth DUNCAN, Megan Alene Cloonan FOLEY, Darren Martin HARVEY, Michael John MUNCHHOF, Michael THOMENIUS, Lawrence Alan REITER
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20200323889
    Abstract: Methods and compositions relating to CDP-proteasome inhibitor conjugates are described herein.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 15, 2020
    Inventors: Alexandra Glucksmann, Lawrence Alan Reiter, Thomas C. Crawford
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20180110791
    Abstract: Methods and compositions relating to CDP-proteasome inhibitor conjugates are described herein.
    Type: Application
    Filed: June 2, 2017
    Publication date: April 26, 2018
    Inventors: Alexandra Glucksmann, Lawrence Alan Reiter, Thomas C. Crawford
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20180015170
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: February 28, 2017
    Publication date: January 18, 2018
    Inventors: Marc Wolfgang, Lawrence Alan Reiter, Thomas C. Crawford, Oliver S. Fetzer
  • ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
    Publication number: 20170291905
    Abstract: Described herein are compounds of Formula (S-I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
    Type: Application
    Filed: September 17, 2015
    Publication date: October 12, 2017
    Applicant: Epizyme, Inc.
    Inventors: Richard Chesworth, Lorna Helen Mitchell, John Emmerson Campbell, Lawrence Alan Reiter, Kerren Kalai Swinger
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20160082111
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: November 13, 2015
    Publication date: March 24, 2016
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Oliver S. Fetzer, Lawrence Alan Reiter, Marc Wolfgang
  • POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
    Publication number: 20140286873
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 25, 2014
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Scott Eliasof, Geeti Gangal, Pei-Sze Ng, Lawrence Alan Reiter
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20140274947
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: September 19, 2013
    Publication date: September 18, 2014
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Oliver S. Fetzer, Lawrence Alan Reiter, Marc Wolfgang
  • Polymer-Agent Conjugates, Particles, Compositions, and Related Methods of Use
    Publication number: 20140193510
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: February 13, 2014
    Publication date: July 10, 2014
    Applicant: CERULEAN PHARMA INC.
    Inventors: Scott Eliasof, Thomas C Crawford, Geeti Gangal, Lawrence Alan Reiter, Pei-Sze Ng
  • POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
    Publication number: 20140099263
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: March 19, 2013
    Publication date: April 10, 2014
    Applicant: CERULEAN PHARMA INC.
    Inventors: Scott Eliasof, Thomas C. Crawford, Geeti Gangal, Lawrence Alan Reiter, Pei-Sze Ng
  • POLYMER-EPOTHILONE CONJUGATES, PARTICLES, COMPOSITIONS AND RELATED METHODS OF USE
    Publication number: 20140072633
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer or neurological deficits. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: May 29, 2013
    Publication date: March 13, 2014
    Applicant: CERULEAN PHARMA INC.
    Inventors: Scott Eliasof, Thomas C. Crawford, Geeti Gangal, Lawrence Alan Reiter, Pei-Sze Ng
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20130261173
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 3, 2013
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Oliver S. Fetzer, Lawrence Alan Reiter, Marc Wolfgang
  • POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
    Publication number: 20130011445
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 10, 2013
    Inventors: Thomas C. Crawford, Scott Eliasof, Geeti Gangal, Pei-Sze Ng, Lawrence Alan Reiter
  • POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
    Publication number: 20120282306
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 8, 2012
    Inventors: Scott Eliasof, Thomas C. Crawford, Geeti Gangal, Lawrence Alan Reiter, Pei-Sze Ng
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20120225825
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: April 6, 2012
    Publication date: September 6, 2012
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Oliver S. Fetzer, Lawrence Alan Reiter, Marc Wolfgang
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20120202772
    Abstract: Methods and compositions relating to CDP-proteasome inhibitor conjugates are described herein.
    Type: Application
    Filed: April 17, 2012
    Publication date: August 9, 2012
    Inventors: Alexandra Glucksmann, Lawrence Alan Reiter, Thomas C. Crawford
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20120058971
    Abstract: Methods and compositions relating to CDP-taxane conjugates are described herein.
    Type: Application
    Filed: August 12, 2011
    Publication date: March 8, 2012
    Applicant: CERULEAN PHARMA INC.
    Inventors: Thomas C. Crawford, Oliver S. Fetzer, Lawrence Alan Reiter, Marc Wolfgang
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
    Publication number: 20120004195
    Abstract: Methods and compositions relating to CDP-proteasome inhibitor conjugates are described herein.
    Type: Application
    Filed: August 12, 2011
    Publication date: January 5, 2012
    Inventors: Alexandra Glucksmann, Lawrence Alan Reiter, Thomas C. Crawford
  • POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE
    Publication number: 20110268658
    Abstract: Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
    Type: Application
    Filed: January 11, 2011
    Publication date: November 3, 2011
    Inventors: Thomas C. Crawford, Scott Eliasof, Geeti Gangal, Pei-Sze Ng, Lawrence Alan Reiter