Abstract: In certain aspects, the disclosed implementations include methods and systems for providing transaction affinity merchant recommendation information performed by transaction affinity platform computing components that execute software stored in a memory. In certain aspects, the disclosed implementations may determine transaction affinity relationship data for transactions associated with a set of account records. Each account record in the set of account records may be associated with a set of users. The disclosed implementations may also determine transaction affinity relationship profiles based on transaction affinity profile parameters that are associated with the transaction affinity relationship data and first transaction data. Further, the disclosed implementations may determine one or more transaction affinity patterns based on the transaction affinity relationship data and the transaction affinity relationship profiles.

Abstract: A computer-implemented method for calibrating audio of a virtual reality device, the method comprising: determining a difference between a perceived tone location and an actual audible tone location, in response to an emitting of the actual audible tone; wherein the tone comprises a spectral tone, and creating and calibrating a user ear model by: emitting the spectral tone at a random time during a simulation by the virtual reality device; determining the perceived tone location during the simulation; and computing an error adjustment for one or more geometric variables of a default ear model based on a result of the determining.

Abstract: A system and method for covering an ultrasound probe by a probe cover application device is provided. The system includes a frame, attachment device, and probe cover sheathing. The frame includes a base having a top side, bottom side, inner edge, and outer edge. The frame includes an extension extending from the top side of the base and substantially perpendicular to the base. The extension includes an inside surface and outside surface. The inner edge of the base and the inside surface of the extension form an opening through the frame. The attachment device is mounted to or integrated with the bottom side of the base of the frame. The probe cover sheathing is bunched up and/or rolled up and positioned against and surrounding the outside surface of the extension. A first closed end of the probe cover sheathing extends over the opening in the extension.

Abstract: A method for fabricating a semiconductor device integrating a multiple patterning scheme includes forming a plurality of mandrels from a base structure, forming a plurality of non-mandrels including a hard mask material having an etch property substantially similar to that of the plurality of mandrels, forming photo-sensitive material or a memorization layer over the plurality of mandrels and the plurality of non-mandrels, and applying an exposure scheme to the photo-sensitive material or the memorization layer to create at least one mandrel cut pattern and at least one non-mandrel cut pattern.

Abstract: The present disclosure relates to a local anesthetic delivery device for delivering anesthetic to a nerve block site comprising a surgical mechanism for establishing a reference plane for identifying the nerve block site, wherein the surgical mechanism establishes the reference plane at the peritoneum and uses a known fixed distance to the nerve plane above to accurately locate the nerve block site and deliver anesthesia.

Abstract: Methods for identifying cancer patients amenable to anti-cancer immunotherapy are provided along with methods of monitoring cancer therapy. Also provided are methods of treating cancer patients amenable to anti-cancer immunotherapy. The methods involve determining the level of CD127<low>PD-1<low>T cells. The patients are treated with an immune checkpoint inhibitor, such as an anti-CTLA-4 antibody, e.g. ipilimumab.

Abstract: The present invention is directed to an RNAi-inducing agent capable of reducing and/or inhibiting the expression of proteins associated with the tight junction complex joining Schlemm's canal endothelial cells (SCEC) in the eye of a subject for use in the prevention and/or treatment of glaucoma. Specifically, the RNAi-inducing agent is capable of reducing and/or inhibiting the expression of proteins expressed in the tight junction complex or supporting the tight junction complex joining Schlemm's canal endothelial cells (SCEC) in the eye of a subject for use in the prevention and/or treatment of glaucoma. Methods using this RNAi-inducing agent are also contemplated.

Abstract: Binding of the transcriptional co-activator, YAP1, to the transcription factor Oct4, induces Sox2. which is a transcription actor necessary for the self-renewal of stem-like cells from non-small cell lung cancer. The WW domain of YAP1 binds to the PPxY motif of Oct4 to induce Sox2. Delivering a peptide corresponding to the WAV domain could prevent the induction of Sox2 and stemness. Similarly, peptides and mimetics of the PPxY motif would be able to inhibit stemness. Disclosed arc compounds that affect the Yap1:Oct4 interaction.

Abstract: An online calibration system for an electrochemical sensor. The calibration system comprises a calibration electrode coupled with a redox species, where the redox species is configured to control a pH of a reference solution local to the calibration electrode, such that when a voltammetric signal is applied to the calibration electrode the output generated from the calibration system is determined by the local environment pH. The output signal from the calibration system is used to calibrate a reference potential generated by a reference system of the electrochemical sensor to correct for drift in the reference potential when the electrochemical sensor is being used. The calibration electrode may be disposed in a reference cell of the electrochemical sensor.

Abstract: A system and method for processing and administering insurance policy premium discounts for mobile device disabling technology to promote safer driver is disclosed. An insurance policy premium discount is determined based on the level of disabling technology implemented by a user on a user's mobile device.

Abstract: In certain aspects, the disclosed implementations include methods and systems for dynamically generating and providing transaction affinity recommendation data. In certain implementations, the transaction affinity recommendation data may include information that identifies a target merchant and associated merchant promotion data that may be generated based on a dynamic analysis of transaction data corresponding to an account record. In some aspects, the disclosed implementations may perform processes that determine adjustments to the merchant recommendation data based on one or more parameters associated with potential next merchants included in the merchant recommendation data. The disclosed implementations may analyze weigh values assigned to the one or more parameters, and based on the weight values and parameter information, may determine a different merchant is to be recommended.

Abstract: The various embodiments provide, a magnesium titanium polymerization procatalyst, and methods for making and using the same.

Abstract: An energy storage system comprising at least one energy storage module adapted to supply electrical energy to a hybrid vehicle. The energy storage module comprises an enclosure, at least one battery array located within the enclosure, and an energy storage controller module located within the enclosure and electrically connected to the battery array. The energy storage module further comprises a compliant tipped thermistor which may be installed within a flexible clip. The thermistor is positioned to monitor the temperature of one or more of the batteries within the energy storage system.

Abstract: A garment includes a fabric base layer and at least one side-emitting optical fiber retained to or integrated with the fabric base layer. The fabric base layer can stretch in the grain and cross grain direction of the fabric base layer. The at least one side-emitting optical fiber is located in at least one light-emitting zone to be located over a targeted body area of the person wearing the garment, and is configured to receive light from a light source and in the at least one light-emitting zone is configured to project light having a therapeutic wavelength toward the targeted body area.

Abstract: Methods for treating fecal incontinence by administering to a subject in need thereof compositions including oxymetazoline as an active ingredient. Kits including compositions of oxymetazoline suitable for topical application, for the treatment of fecal incontinence.

Abstract: In certain aspects, the disclosed implementations include methods and systems for dynamically generating and providing transaction affinity recommendation data. In certain implementations, the transaction affinity recommendation data may include information that identifies a target merchant and associated merchant promotion data that may be generated based on a dynamic analysis of transaction data corresponding to an account record. The disclosed implementations may determine temporal relationships between pairs of sequential transactions corresponding to the account record, and based on such relationships, may identify pairs of transactions involving separate merchants. The disclosed implementations may determine affinity relationships associated with one or more pairs of the temporally related transactions and a target merchant, and based on such relationships, generate and provide the transaction affinity recommendation data.

Abstract: Dentifrice containing silica particles having a d50 median particle size from 4 to 25 ?m, a BET surface area of less than 10 m2/g, and a total mercury intrusion pore volume from 0.2 to 1.5 cc/g, are disclosed.

Abstract: Method and system are disclosed for determining conditions of components that are removably coupled to articles of personal protection equipment (PPE) by tracking the components against predetermined criteria.

Abstract: Vehicle suspension systems are described herein. An example wheel steering apparatus includes a steering actuator to couple to a rear axle, a tie rod, and a transfer link to couple the steering actuator and the tie rod. The steering actuator is positioned on a first side of a first longitudinal axis of the rear axle and the tie rod positioned on a second side of the first longitudinal axis of the rear axle opposite the first side.

Abstract: An approach for determining a veracity of a reported event is provided. In an embodiment, a set of predictor variables is retrieved from a selected use case. Each of these predictor values is a condition that indicates the veracity of the reported event. In addition, a set of hidden predictor variables is generated from a set of unstructured documents related to the reported event using a hidden Markov model that is based on the predictor variables using a cognitive system. These hidden predictor variables are combined with the set of predictor variables to generate a set of updated predictor variables. These updated predictor variables are used by the cognitive system to return a determination of the veracity of the reported event.