Patents by Inventor Lawrence B. Snyder

Lawrence B. Snyder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C Virus Inhibitors
    Publication number: 20080044380
    Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
    Type: Application
    Filed: August 8, 2007
    Publication date: February 21, 2008
    Inventors: Carol Bachand, Makonen Belema, Daniel H. Deon, Andrew C. Good, Jason Goodrich, Clint A. James, Rico Lavoie, Omar D. Lopez, Alain Martel, Nicholas A. Meanwell, Van N. Nguyen, Jeffrey Lee Romine, Edward H. Ruediger, Lawrence B. Snyder, Denis R. St. Laurent, Fukang Yang, David R. Langley, Lawrence G. Hamann
  • Hepatitis C Virus Inhibitors
    Publication number: 20080044379
    Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
    Type: Application
    Filed: August 8, 2007
    Publication date: February 21, 2008
    Inventors: Carol Bachand, Makonen Belema, Daniel H. Deon, Andrew C. Good, Jason Goodrich, Clint A. James, Rico Lavoie, Omar D. Lopez, Alain Martel, Nicholas A. Meanwell, Van N. Nguyen, Jeffrey Lee Romine, Edward H. Ruediger, Lawrence B. Snyder, Denis R. St. Laurent, Fukang Yang, David R. Langley, Lawrence G. Hamann
  • Iminothiazolidinones as inhibitors of HCV replication
    Patent number: 7183302
    Abstract: Compounds having the structure of formula I are described wherein R, R?, R1, R2, and R3 are as defined in the specification. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular the function of the HCV NS5A protein.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: February 27, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jeffrey Lee Romine, Scott W. Martin, Lawrence B. Snyder, Michael Serrano-Wu, Milind Deshpande, Darren Whitehouse, Julie Lemm, Donald O'Boyle, Min Gao, Richard Colonno
  • Isoxazolinone antibacterial agents
    Patent number: 6465456
    Abstract: This invention describes isoxazolinone derivatives which possess antibacterial activity and are useful in the treatment of bacterial diseases. More particularly, new isoxazolinones are provided having the general formula I wherein R1, R2, R3, L and L1 are as described in the specification.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: October 15, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Dane M. Springer, Jason T. Goodrich, Zhaoxing Meng, Lawrence B. Snyder
  • Novel isoxazolinone antibacterial agents
    Publication number: 20020094984
    Abstract: This invention describes isoxazolinone derivatives which possess antibacterial activity and are useful in the treatment of bacterial diseases.
    Type: Application
    Filed: February 13, 2001
    Publication date: July 18, 2002
    Inventors: Lawrence B. Snyder, Zhizhen Zheng
  • Isoxazolinone antibacterial agents
    Patent number: 6420349
    Abstract: This invention describes isoxazolinone compounds which possess antibacterial activity and are useful in the treatment of bacterial diseases.
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: July 16, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Lawrence B. Snyder, Zhizhen Zheng
  • Novel isoxazolinone antibacterial agents
    Publication number: 20020040142
    Abstract: This invention describes isoxazolinone derivatives which possess antibacterial activity and are useful in the treatment of bacterial diseases.
    Type: Application
    Filed: June 28, 2001
    Publication date: April 4, 2002
    Inventors: Dane M. Springer, Jason T. Goodrich, Zhaoxing Meng, Lawrence B. Snyder
  • Total synthesis of taxol and analogues thereof
    Patent number: 5597931
    Abstract: The present invention provides three basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogues of taxol and nortaxol.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: January 28, 1997
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, John Masters, Wendy Young, J. Thomas Link, Richard Isaacs, Lawrence B. Snyder
  • Camptothecin analogues and methods of preparation thereof
    Patent number: 5525731
    Abstract: Substituted analogues of camptothecin possessing cytotoxic activity towards cancer cells, of the general structure: ##STR1## wherein E is H, CO.sub.2 R, CONH.sub.2, CONHR, CONR.sub.2, or CN; R.sup.0 and R.sup.1 are independently the same or different and are H, or a linear or branched alkyl, linear or branched alkylaryl, hydroxyalkyl or aryl group; R.sup.2, R.sup.3 and R.sup.4 are independently the same or different and are H, or a linear or branched alkyl, linear or branched alkylaryl, hydroxyalkyl or aryl group; R.sup.5, R.sup.6, R.sup.7, R.sup.8 and R.sup.9 are independently the same or different and are H, or a linear or branched alkyl, linear or branched alkylaryl or aryl group, or an alkoxy, aryloxy, hydroxyalkyl, C-glycal, nitro, cyano or aminoalkoxy group, or CO.sub.2 R, Cl, F, Br, I, SR.sup.10, NR.sup.11 R.sup.12 or OR.sup.13 ; R is H, an alkyl, aryl, alkylaryl or hydroxyalkyl group; R.sup.10, R.sup.11 and R.sup.
    Type: Grant
    Filed: October 25, 1994
    Date of Patent: June 11, 1996
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Lawrence B. Snyder