Patents by Inventor Lawrence Blecka
Lawrence Blecka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8992833Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: GrantFiled: December 17, 2012Date of Patent: March 31, 2015Assignee: Bio Rad-Laboratories, Inc.Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
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Patent number: 8449687Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.Type: GrantFiled: February 13, 2012Date of Patent: May 28, 2013Assignee: Bio-Rad Laboratories, Inc.Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
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Patent number: 8357537Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: GrantFiled: April 26, 2011Date of Patent: January 22, 2013Assignee: Bio-Rad Laboratories, Inc.Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
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Publication number: 20120138099Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.Type: ApplicationFiled: February 13, 2012Publication date: June 7, 2012Applicant: BIO-RAD LABORATORIES, INC.Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
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Patent number: 8136539Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.Type: GrantFiled: May 9, 2008Date of Patent: March 20, 2012Assignee: Bio-Rad Laboratories, Inc.Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
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Publication number: 20110262896Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: ApplicationFiled: April 26, 2011Publication date: October 27, 2011Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
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Patent number: 7955555Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: GrantFiled: April 6, 2007Date of Patent: June 7, 2011Assignee: Bio-Rad Laboratories, Inc.Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
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Publication number: 20080302393Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.Type: ApplicationFiled: May 9, 2008Publication date: December 11, 2008Applicant: Bio-Rad Laboratories, Inc.Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
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Publication number: 20070189925Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: ApplicationFiled: April 6, 2007Publication date: August 16, 2007Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
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Patent number: 7220385Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: GrantFiled: July 19, 2004Date of Patent: May 22, 2007Assignee: Bio-Rad Laboratories, Inc.Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
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Publication number: 20050123445Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.Type: ApplicationFiled: July 19, 2004Publication date: June 9, 2005Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
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Publication number: 20050048468Abstract: A serum in which are dissolved at least two heterologous antibodies, which are independently IgG or IgM and which specifically bind to different antigens, serves as a calibrator for multi-analyte immunoassays.Type: ApplicationFiled: August 27, 2003Publication date: March 3, 2005Applicant: Bio-Rad Laboratories, Inc.Inventors: Peilin Chen, Hao Yu, Lawrence Blecka, Steve Binder