Patents by Inventor Lawrence Blecka

Lawrence Blecka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8992833
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: March 31, 2015
    Assignee: Bio Rad-Laboratories, Inc.
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
  • Patent number: 8449687
    Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: May 28, 2013
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
  • Patent number: 8357537
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: January 22, 2013
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
  • Publication number: 20120138099
    Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 7, 2012
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
  • Patent number: 8136539
    Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: March 20, 2012
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
  • Publication number: 20110262896
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Application
    Filed: April 26, 2011
    Publication date: October 27, 2011
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
  • Patent number: 7955555
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: June 7, 2011
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken J. Lafredo
  • Publication number: 20080302393
    Abstract: Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.
    Type: Application
    Filed: May 9, 2008
    Publication date: December 11, 2008
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Nasser Jafari, Lawrence Blecka, Chris Tsai
  • Publication number: 20070189925
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Application
    Filed: April 6, 2007
    Publication date: August 16, 2007
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
  • Patent number: 7220385
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Grant
    Filed: July 19, 2004
    Date of Patent: May 22, 2007
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
  • Publication number: 20050123445
    Abstract: The present invention provides a system and method for the simultaneous detection of multiple analytes in a sample. The detection system includes a housing that holds a reagent carousel rotatably coupled thereto. Further included in the housing is an incubator carousel rotatably coupled thereto. The housing also includes magnetic material that is associated with the incubation carousel for assisting in separation beads from reagent and wash solution. A robot, associated with the housing is configured to manipulate at least either the reagent carousel or the incubator carousel and transfer materials therebetween. Reaction vessels hold samples and reaction vessels handlers move the reaction vessels. Sample analysis is determined by at least one laser based detector.
    Type: Application
    Filed: July 19, 2004
    Publication date: June 9, 2005
    Inventors: Lawrence Blecka, Larry Seamer, Sachi Rastogi, Chris Tsai, Nasser Jafari, Ken Lafredo
  • Publication number: 20050048468
    Abstract: A serum in which are dissolved at least two heterologous antibodies, which are independently IgG or IgM and which specifically bind to different antigens, serves as a calibrator for multi-analyte immunoassays.
    Type: Application
    Filed: August 27, 2003
    Publication date: March 3, 2005
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Peilin Chen, Hao Yu, Lawrence Blecka, Steve Binder