Patents by Inventor Lawrence Boise

Lawrence Boise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER WITH A COMBINATION OF GLUCOSE MODULATORS AND BCL-2 INHIBITORS
    Publication number: 20160113925
    Abstract: This disclosure relates to treating or preventing cancers, such as hematological malignancies, by administering a compound that binds BCL2 and one or more compounds that inhibit glucose or glutamine metabolism. In certain embodiments, the compounds that inhibit glucose metabolism are ritonavir optionally in combination with 6-diazo-5-oxo-L-norleucine or any derivative, prodrugs, or salts of these compounds. Contemplated BCL2 binding compounds are ABT-199 (venetoclax), ABT-263 (navitoclax), or ABT-737.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 28, 2016
    Applicant: EMORY UNIVERSITY
    Inventors: Malathy Shanmugam, Richa Bajpai, Lawrence Boise