Abstract: A method and system may provide automated messages to a patient to increase the likelihood that the patient adheres to a medication regimen. A reinforcement learning engine determines the patient's barriers to adherence and transmits messages generated to address those barriers. The reinforcement learning engine constantly receives feedback from the patient and adjusts the messages that are transmitted to the patient, for example, when the patient's barrier to adherence changes, when the patient incorrectly identifies his barrier to adherence, and/or when the patient becomes desensitized to receiving the same message over and over again.