Patents by Inventor Lawrence C. Dugan

Lawrence C. Dugan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-channel optical detection system and method for multi-chamber assays
    Patent number: 11975321
    Abstract: A multi-channel optical detection system includes a base unit adapted to receive a multi-chamber assay cartridge having a plurality of reaction chambers loaded with a sample and an optical detection reagent, and an optical detection unit having a multi-channel optical block having a plurality of detection channels each with an associated light source, and an optic sensor. The optical detection unit is connectable to the base unit so that interrogation ports of the detection channels are optically aligned with optically transparent windows of the reaction chambers of a loaded cartridge, so that upon initialization, light sources are activated to interrogate reaction products in the reaction chambers and detect the optical responses therefrom.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: May 7, 2024
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Lawrence C. Dugan, William J. Benett, Elizabeth K. Wheeler
  • MULTI-CHANNEL OPTICAL DETECTION SYSTEM AND METHOD FOR MULTI-CHAMBER ASSAYS
    Publication number: 20190299209
    Abstract: A multi-channel optical detection system includes a base unit adapted to receive a multi-chamber assay cartridge having a plurality of reaction chambers loaded with a sample and an optical detection reagent, such as for example a fluorescence detection reagent, and an optical detection unit having a multi-channel optical block having a plurality of detection channels each with an associated light source, and an optic sensor. The optical detection unit is connectable to the base unit so that interrogation ports of the detection channels are optically aligned with optically transparent windows of the reaction chambers of a loaded cartridge.
    Type: Application
    Filed: March 27, 2019
    Publication date: October 3, 2019
    Inventors: Lawrence C. Dugan, William J. Benett, Elizabeth K. Wheeler
  • Apparatus for point-of-care detection of nucleic acid in a sample
    Patent number: 9315858
    Abstract: Provided herein are methods and apparatus for detecting a target nucleic acid in a sample and related methods and apparatus for diagnosing a condition in an individual. The condition is associated with presence of nucleic acid produced by certain pathogens in the individual.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: April 19, 2016
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Jane P. Bearinger, Lawrence C. Dugan
  • Methods for point-of-care detection of nucleic acid in a sample
    Patent number: 9222126
    Abstract: Provided herein are methods and apparatus for detecting a target nucleic acid in a sample and related methods and apparatus for diagnosing a condition in an individual. The condition is associated with presence of nucleic acid produced by certain pathogens in the individual.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: December 29, 2015
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Jane P. Bearinger, Lawrence C. Dugan
  • APPARATUS FOR POINT-OF-CARE DETECTION OF NUCLEIC ACID IN A SAMPLE
    Publication number: 20110294199
    Abstract: Provided herein are methods and apparatus for detecting a target nucleic acid in a sample and related methods and apparatus for diagnosing a condition in an individual. The condition is associated with presence of nucleic acid produced by certain pathogens in the individual.
    Type: Application
    Filed: May 25, 2011
    Publication date: December 1, 2011
    Inventors: Jane P. BEARINGER, Lawrence C. Dugan
  • METHODS FOR POINT-OF-CARE DETECTION OF NUCLEIC ACID IN A SAMPLE
    Publication number: 20110294112
    Abstract: Provided herein are methods and apparatus for detecting a target nucleic acid in a sample and related methods and apparatus for diagnosing a condition in an individual. The condition is associated with presence of nucleic acid produced by certain pathogens in the individual.
    Type: Application
    Filed: May 25, 2011
    Publication date: December 1, 2011
    Inventors: Jane P. Bearinger, Lawrence C. Dugan