Patents by Inventor Lawrence G. Pape

Lawrence G. Pape has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4328803
    Abstract: This disclosure is directed to improved opthalmological surgical procedures on the human eyeball characterized by initially utilizing ultra-pure hyaluronic acid in the form of a solution containing the sodium salt thereof, in a sufficient concentration thereof to protect delicate eye tissue and cells, e.g., 0.5 to 1.0 wt. % and higher, and thereafter, significantly diluting the concentration thereof in the aqueous media (natural and/or synthetic) within the anterior segment of the eye viz, in situ, so as to arrive at a concentration of said sodium salt of hyaluronic acid of less than 0.5 wt. % and more usually from about 0.1 to about 0.3 wt. % prior to closure. Hence a significant dilution from the initial higher concentrations by a factor of at least about 2:1 and more usually from about 3:1 to about 10:1 is effected. Hence the concentration of said sodium hyaluronate in the natural and/or synthetic aqueous media left within the eyeball at the surgical site after closure of the procedure ranges from about 0.
    Type: Grant
    Filed: October 20, 1980
    Date of Patent: May 11, 1982
    Assignee: Opthalmic Systems, Inc.
    Inventor: Lawrence G. Pape