Patents by Inventor Lawrence Hylton Patterson

Lawrence Hylton Patterson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxylation activated drug release
    Patent number: 6794384
    Abstract: The present invention concerns prodrugs whose aromatic oxidation, particularly their enzymatic aromatic hydroxylation, results in their activation by the release of a drug moiety. It particularly concerns anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the P-450 enzyme CYP1B1. Also provided are methods of detection of aromatic oxidation activity.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: September 21, 2004
    Assignee: De Montfort University
    Inventors: Gerard Andrew Potter, Lawrence Hylton Patterson, Michael Danny Burke
  • Hydroxylation activated prodrugs
    Patent number: 6677383
    Abstract: The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: January 13, 2004
    Assignee: De Montfort University
    Inventors: Gerard Andrew Potter, Lawrence Hylton Patterson, Michael Danny Burke, Paul Crispin Butler
  • HYDROXYLATION ACTIVATED DRUG RELEASE
    Publication number: 20020037296
    Abstract: The present invention concerns prodrugs whose aromatic oxidation, particularly their enzymatic aromatic hydroxylation, results in their activation by the release of a drug moiety. It particularly concerns anti-tumour prodrugs and those which are specifically activated by the hydroxylation activity of the P-450 enzyme CYP1B1.
    Type: Application
    Filed: July 14, 1998
    Publication date: March 28, 2002
    Inventors: GERALD ANDREW POTTER, LAWRENCE HYLTON PATTERSON, MICHAEL DANNY BURKE
  • Hydroxylation activated prodrugs
    Patent number: 6346550
    Abstract: The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumour prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: February 12, 2002
    Inventors: Gerald Andrew Potter, Lawrence Hylton Patterson, Michael Danny Burke
  • Hydroxylation activated prodrugs
    Publication number: 20010021717
    Abstract: The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
    Type: Application
    Filed: January 19, 2001
    Publication date: September 13, 2001
    Applicant: De Montfort University
    Inventors: Gerald Andrew Potter, Lawrence Hylton Patterson, Michael Danny Burke
  • Hydroxylation activated prodrugs
    Patent number: 6214886
    Abstract: The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumour prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: April 10, 2001
    Assignee: DeMontfort University, The Gateway
    Inventors: Gerald Andrew Potter, Lawrence Hylton Patterson, Michael Danny Burke