Patents by Inventor Lawrence J. Wangh

Lawrence J. Wangh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LATE-PCR
    Publication number: 20040053254
    Abstract: A non-symmetric polymerase chain reaction (PCR) amplification method employing a limiting primer in low concentration whose concentration-adjusted melting point at least equals, and preferably exceeds, that of the excess primer, the latter in turn not being more than 25° C. below the melting temperature of the amplicon. Assays employing such amplification and labeled hybridization probes, including assays that include a detection step following primer extension or a low-temperature probe, or both. Kits for performing such assays and primer or primer-and-probe sets for performing the foregoing amplifications and assays.
    Type: Application
    Filed: December 17, 2002
    Publication date: March 18, 2004
    Inventors: Lawrence J. Wangh, Kenneth Pierce, Cristina Hartshorn, John Rice, J. Aquiles Sanchez
  • PRENATAL SCREENING
    Publication number: 20020178462
    Abstract: The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Application
    Filed: January 6, 1999
    Publication date: November 28, 2002
    Inventor: LAWRENCE J. WANGH
  • Product and method for swelling a cell nucleus without DNA replication
    Publication number: 20020132344
    Abstract: The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Application
    Filed: March 14, 2002
    Publication date: September 19, 2002
    Inventor: Lawrence J. Wangh
  • Activating egg extracts and method of preparation
    Patent number: 6245567
    Abstract: The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: June 12, 2001
    Assignee: Brandeis University
    Inventor: Lawrence J. Wangh
  • Activation of sperm nuclei and activation assays
    Patent number: 5773217
    Abstract: The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: June 30, 1998
    Assignee: Brandeis University
    Inventor: Lawrence J. Wangh
  • In vitro activation of human fetal cells
    Patent number: 5651992
    Abstract: The present invention concerns products and methods particularly useful for activating and analyzing non-dividing cell nuclei. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Grant
    Filed: February 1, 1994
    Date of Patent: July 29, 1997
    Assignee: Brandeis University
    Inventor: Lawrence J. Wangh
  • In vitro activation of a nucleus
    Patent number: 5480772
    Abstract: Products and methods particularly useful for activating and analyzing the nuclei and nucleic acids of human fetal red blood cells or cells found in amniotic fluid thereby facilitating prenatal screening are described. The featured products include activating egg extracts, cytostatic factor (CSF) extracts, kits containing these extracts, and a microchamber microscope slide useful in analyzing nucleus activation.
    Type: Grant
    Filed: February 3, 1993
    Date of Patent: January 2, 1996
    Assignee: Brandeis University
    Inventor: Lawrence J. Wangh