Patents by Inventor Lawrence Joseph Heinz, II

Lawrence Joseph Heinz, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD73 inhibitors
    Patent number: 11028074
    Abstract: The present invention provides 5-[5]-[2-cycloalkyl]-6-pyridazin-3-yl]-1H-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: June 8, 2021
    Assignee: Eli Lilly and Company
    Inventors: Robert Dean Dally, Maria Cristina Garcia Paredes, Lawrence Joseph Heinz, II, Jennifer Marie Howell, Frank George Njoroge, Yan Wang, Genshi Zhao
  • CD73 INHIBITORS
    Publication number: 20210002257
    Abstract: The present invention provides 5-[5]-[2-cycloalkyl]-6-pyridazin-3-yl]-1H-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer.
    Type: Application
    Filed: February 22, 2019
    Publication date: January 7, 2021
    Inventors: Robert Dean DALLY, Maria Cristina GARCIA PAREDES, Lawrence Joseph HEINZ II, Jennifer Marie HOWELL, Frank George NJOROGE, Yan WANG, Genshi ZHAO
  • NOVEL PYRIDYLOXYACETYL TETRAHYDROISOQUINOLINE COMPOUNDS USEFUL AS NAMPT INHIBITORS
    Publication number: 20160229835
    Abstract: The present invention provides novel pyridyloxyacetyl tetrahydroisoquinoline compounds that inhibit NAMPT and may be useful in the treatment of cancer.
    Type: Application
    Filed: October 3, 2014
    Publication date: August 11, 2016
    Inventors: Timothy Paul Burkholder, Miriam Filadelfa Del Prado, Maria Carmen Fernandez, Lawrence Joseph Heinz, II, Lourdes Prieto, Genshi Zhao