Patents by Inventor Lawrence Kirschner

Lawrence Kirschner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230289941
    Abstract: A method for predicting an occurrence of a structural feature in a core image using a backpropagation-enabled process trained by inputting a set of training images of a core image, iteratively computing a prediction of the probability of occurrence of the structural feature for the set of training images and adjusting the parameters in the backpropagation-enabled model until the model is trained. The trained backpropagation-enabled model is used to predict the occurrence of the structural features in non-training core images. The set of training images may include non-structural features and/or simulated data, including augmented images and synthetic images.
    Type: Application
    Filed: June 22, 2021
    Publication date: September 14, 2023
    Inventors: David Lawrence KIRSCHNER, John SOLUM
  • Publication number: 20230145880
    Abstract: A method for predicting an occurrence of a geological feature in a geologic core image uses a backpropagation-enabled segmentation process trained by inputting multiple training geologic core images and a set of associated labels of geological features, iteratively computing a prediction of the probability of occurrence of the geological feature for the training images and adjusting the parameters in the backpropagation-enabled segmentation model until the model is trained. The trained backpropagation-enabled segmentation model is used to predict the occurrence of the geological features in non-training geologic core images. Geological features to be predicted with this method include structural features (such as veins, fractures, bedding contacts, etc.), and stratigraphic features (such as lithologic types, sedimentary structures, sedimentary facies, etc.).
    Type: Application
    Filed: March 23, 2021
    Publication date: May 11, 2023
    Inventors: John SOLUM, Oriol FALIVENE ALDEA, Pedram ZARIAN, David Lawrence KIRSCHNER, Neal Christian AUCHTER, Antonino CILONA
  • Patent number: 6759525
    Abstract: The present invention provides compositions and methods useful in the diagnosis and prognosis of Carney complex (CNC), as well as methods and compositions for the identification of compounds useful in the treatment and/or prevention of CNC. In addition, the present invention provides compositions and methods useful in the diagnosis and treatment of conditions associated with skin pigmentation defects, including but not limited to freckling, as well as endocrine tumors including, but not limited to adrenal and pituitary tumors. In addition, the present invention provides methods and compositions for the diagnosis and treatment of various types of cancers associated with abnormal activity of protein kinase A. In particular, the present invention provides genetic and other sequence information, as well as assay systems that will find use in these and related areas.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: July 6, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Constantine Stratakis, Lawrence Kirschner
  • Publication number: 20030022180
    Abstract: The present invention provides compositions and methods useful in the diagnosis and prognosis of Carney complex (CNC), as well as methods and compositions for the identification of compounds useful in the treatment and/or prevention of CNC. In addition, the present invention provides compositions and methods useful in the diagnosis and treatment of conditions associated with skin pigmentation defects, including but not limited to freckling, as well as endocrine tumors including, but not limited to adrenal and pituitary tumors. In addition, the present invention provides methods and compositions for the diagnosis and treatment of various types of cancers associated with abnormal activity of protein kinase A. In particular, the present invention provides genetic and other sequence information, as well as assay systems that will find use in these and related areas.
    Type: Application
    Filed: August 23, 2001
    Publication date: January 30, 2003
    Applicant: The Government Of USA, Department Of Health And Human Services
    Inventors: Constantine Stratakis, Lawrence Kirschner
  • Patent number: 5674529
    Abstract: Multiparticulate controlled release preparations incorporating an alkalinizing potassium salt, preferably potassium bicarbonate, as an active ingredient, which are suitable for forming pharmaceutical dosage forms for oral administration. Such dosage forms are useful for potassium supplementation and for the treatment of degenerative bone or cardiovascular diseases, e.g., osteoporosis and hypertension.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 7, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Herman Marder, Lawrence Kirschner, John J. Steinke, Andrew D. Kurtz, Poul Bertelsen, Nils Gjerlov Hansen, Thyge Borup Hjorth
  • Patent number: 5509971
    Abstract: A process for removing coatings from hard surfaces includes blasting the surfaces with a free-flowing particulate blast media entrained in a pressurized fluid, the blast media containing a major amount of relatively soft granular abrasive particles which have a Mohs hardness of less than 4.0 and a minor amount of free-flowing, separate relatively hard granular abrasive particles which have a hardness of greater than 5.0 on the Mohs scale, the granular abrasives having a particle size of from about 10 to about 2000 microns and being devoid of crystalline silica material.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: April 23, 1996
    Assignee: Church & Dwight Co., Inc.
    Inventor: Lawrence Kirschner
  • Patent number: 5505749
    Abstract: A blast media for removing coatings from hard surfaces such as steel includes a major amount of a granular relatively soft abrasive having a Mohs hardness of less than 4 and a minor portion of a granular hard abrasive having a Mohs hardness of greater than 5.
    Type: Grant
    Filed: November 8, 1993
    Date of Patent: April 9, 1996
    Assignee: Church & Dwight Co., Inc.
    Inventors: Lawrence Kirschner, Benny S. Yam
  • Patent number: 5445805
    Abstract: A large size, small surface area, granular crystalline potassium bicarbonate product suitable for application as an active ingredient in pharmaceutical oral unit dosage forms useful for the treatment of various degenerative bone and cardiovascular diseases, particularly osteoporosis or hypertension, comprising potassium bicarbonate crystals having a mean particle size of at least 350 microns and a specific B.E.T. surface area less than 0.02 m.sup.2 /gram. A process for preparing such product is further provided, in which a solution of potassium bicarbonate is fed to a slurry of potassium bicarbonate crystals in a crystallizer and the temperatures and concentrations of the potassium bicarbonate in the feed solution and the crystallizer slurry are so regulated, and the residence time and degree of agitation in the crystallizer are so controlled, that the desired large size, small surface area potassium bicarbonate crystals are produced.
    Type: Grant
    Filed: May 6, 1993
    Date of Patent: August 29, 1995
    Assignee: Church & Dwight Co., Inc.
    Inventors: William Zuccarello, Andrew D. Kurtz, Lawrence Kirschner, Herman Marder
  • Patent number: 5443822
    Abstract: This invention provides an improved antiperspirant-deodorant cosmetic stick product. An essential aspect of the cosmetic stick product is a content of particulate antiperspirant and alkali metal bicarbonate ingredients, at least one of which has ingredient particle surfaces coated with a hydrophilic organic polymer.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: August 22, 1995
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wendy R. Greczyn, M. Stephen Lajoie, John R. Berschied, Lawrence Kirschner
  • Patent number: 5439493
    Abstract: A blast media for removing coatings from steel comprises a major amount of a granular relatively soft abrasive such as trona, i.e., natural sodium sesquicarbonate, and a minor portion of a granular hard abrasive such as aluminum oxide.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: August 8, 1995
    Assignee: Church & Dwight Co., Inc.
    Inventor: Lawrence Kirschner
  • Patent number: 5354553
    Abstract: This invention provides an improved process for producing an antiperspirant-deodorant cosmetic stick product. An essential aspect of the process improvement is a phased order of ingredient addition and blending of formulation ingredients under controlled temperature conditions. Another essential aspect is the incorporation of particulate antiperspirant and alkali metal bicarbonate ingredients, at least one of which has ingredient particle surfaces coated with a hydrophilic organic polymer.
    Type: Grant
    Filed: December 8, 1992
    Date of Patent: October 11, 1994
    Assignee: Church & Dwight Co., Inc
    Inventors: Wendy R. Greczyn, M. Stephen Lajoie, John R. Berschied, Lawrence Kirschner
  • Patent number: 5232514
    Abstract: An alkaline blast cleaning system for aluminum surfaces which avoids discoloring or tarnishing of the aluminum surfaces, is comprised of an alkali metal bicarbonate having a particle size of from about 50 to about 1000 and an aqueous solution of sodium silicate, the sodium silicate having an SiO.sub.2 :Na.sub.2 O ratio of from about 2.44 to about 3.22:1 and being present in the aqueous solution in a corrosion inhibiting concentration of from about 100 to about 1000 ppm., the pH of the solution ranging from about 8.1 to about 8.3.
    Type: Grant
    Filed: October 10, 1991
    Date of Patent: August 3, 1993
    Assignee: Church & Dwight Co., Inc.
    Inventors: Jack H. Van Sciver, Lawrence Kirschner
  • Patent number: 5230185
    Abstract: A conventional blasting apparatus is modified to provide a separate source of line air to a blast pot through a pressure regulator to provide a greater pressure in the blast pot than is provided to the conveying hose. This differential pressure is maintained by an orifice having a predetermined area situated between the blast pot and the conveying hose. This orifice provides an exit for the blast medium and a relatively small quantity of air from the blast pot to the conveying hose, and ultimately to the nozzle and finally the workpiece. The differential air pressure, typically operating between 1.0 and 15.0 psi with an orifice having an appropriate area, yields acceptable media flow rates in a controlled manner.
    Type: Grant
    Filed: November 19, 1991
    Date of Patent: July 27, 1993
    Assignee: Church & Dwight Co., Inc.
    Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
  • Patent number: 5160547
    Abstract: Blasting media for removing coatings from sensitive metal and composite surfaces, and a process useful therewith, wherein the blasting media comprise mixtures of water-soluble crystalline sodium bicarbonate particles having average particle sizes of from 100-500 microns.
    Type: Grant
    Filed: May 17, 1991
    Date of Patent: November 3, 1992
    Assignee: Church & Dwight Co., Inc.
    Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
  • Patent number: 5112406
    Abstract: Blasting media for removing coatings from sensitive metal and composite surfaces, and a process useful therewith, wherein the blasting media comprise mixtures of water-soluble crystalline sodium sulfate particles having average particle sizes of from 100 to 250 microns, in admixture with flow/anticaking agents.
    Type: Grant
    Filed: December 3, 1991
    Date of Patent: May 12, 1992
    Assignee: Church & Dwight Co., Inc.
    Inventors: Michael S. Lajoie, Lawrence Kirschner
  • Patent number: 5083402
    Abstract: Conventional industrial pressure blasting apparatus is modified to allow a controlled pressure on the blast pot that is greater than the pressure on the line where less aggressive abrasive media and air are mixed for conveying the mixture to the nozzle and then to the workpiece. A media control device, with a fixed but readily variable area, is placed between the blast pot and the media/air mixing line to meter the media flow and maintain a positive pressure differential between the blast pot and the line. Adjusting the pressure differential allows control of the weight ratio of the media-to-air flow to between about 0.05 to 0.25.
    Type: Grant
    Filed: April 4, 1991
    Date of Patent: January 28, 1992
    Assignee: Church & Dwight Co., Ind.
    Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
  • Patent number: 5081799
    Abstract: Conventional industrial pressure blasting apparatus is modified to allow a controlled pressure on the blast pot that is greater than the pressure on the line where the media and air are mixed for conveying the mixture to the nozzle and then to the workpiece. A media control device, with a fixed but readily variable area, is placed between the blast pot and the media/air mixing line to meter the media flow and maintain the pressure differential between the blast pot and the line. This allows control of the media flow when low flow rates, below about 10 pounds per minute, are required.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: January 21, 1992
    Assignee: Church & Dwight Co., Inc.
    Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
  • Patent number: 4265790
    Abstract: Dry blended carbonate or phosphate-based laundry detergents are prepared by adding to unhydrated or partially hydrated builder salts, a pH buffering compound and a detergent active compound, together with other formulating agents, coarse, hydrous granular water soluble silicate particles, the silicate particles passing a 10 mesh screen and about 95% of the particles are retained on a 100 mesh screen, according to the disclosed method. Dry blended laundry detergents so formulated are substantially completely free of insoluble product lumps when used in cold wash water in the temperature range of 35.degree.-75.degree. F.
    Type: Grant
    Filed: August 9, 1979
    Date of Patent: May 5, 1981
    Assignee: Church & Dwight Co., Inc.
    Inventors: Anthony E. Winston, Francis R. Cala, Stephen P. Lengyel, Lawrence Kirschner, Dragomir Bracilovic