Patents by Inventor Lawrence Kirschner
Lawrence Kirschner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230289941Abstract: A method for predicting an occurrence of a structural feature in a core image using a backpropagation-enabled process trained by inputting a set of training images of a core image, iteratively computing a prediction of the probability of occurrence of the structural feature for the set of training images and adjusting the parameters in the backpropagation-enabled model until the model is trained. The trained backpropagation-enabled model is used to predict the occurrence of the structural features in non-training core images. The set of training images may include non-structural features and/or simulated data, including augmented images and synthetic images.Type: ApplicationFiled: June 22, 2021Publication date: September 14, 2023Inventors: David Lawrence KIRSCHNER, John SOLUM
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Publication number: 20230145880Abstract: A method for predicting an occurrence of a geological feature in a geologic core image uses a backpropagation-enabled segmentation process trained by inputting multiple training geologic core images and a set of associated labels of geological features, iteratively computing a prediction of the probability of occurrence of the geological feature for the training images and adjusting the parameters in the backpropagation-enabled segmentation model until the model is trained. The trained backpropagation-enabled segmentation model is used to predict the occurrence of the geological features in non-training geologic core images. Geological features to be predicted with this method include structural features (such as veins, fractures, bedding contacts, etc.), and stratigraphic features (such as lithologic types, sedimentary structures, sedimentary facies, etc.).Type: ApplicationFiled: March 23, 2021Publication date: May 11, 2023Inventors: John SOLUM, Oriol FALIVENE ALDEA, Pedram ZARIAN, David Lawrence KIRSCHNER, Neal Christian AUCHTER, Antonino CILONA
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Patent number: 6759525Abstract: The present invention provides compositions and methods useful in the diagnosis and prognosis of Carney complex (CNC), as well as methods and compositions for the identification of compounds useful in the treatment and/or prevention of CNC. In addition, the present invention provides compositions and methods useful in the diagnosis and treatment of conditions associated with skin pigmentation defects, including but not limited to freckling, as well as endocrine tumors including, but not limited to adrenal and pituitary tumors. In addition, the present invention provides methods and compositions for the diagnosis and treatment of various types of cancers associated with abnormal activity of protein kinase A. In particular, the present invention provides genetic and other sequence information, as well as assay systems that will find use in these and related areas.Type: GrantFiled: August 23, 2001Date of Patent: July 6, 2004Assignee: The United States of America as represented by the Department of Health and Human ServicesInventors: Constantine Stratakis, Lawrence Kirschner
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Publication number: 20030022180Abstract: The present invention provides compositions and methods useful in the diagnosis and prognosis of Carney complex (CNC), as well as methods and compositions for the identification of compounds useful in the treatment and/or prevention of CNC. In addition, the present invention provides compositions and methods useful in the diagnosis and treatment of conditions associated with skin pigmentation defects, including but not limited to freckling, as well as endocrine tumors including, but not limited to adrenal and pituitary tumors. In addition, the present invention provides methods and compositions for the diagnosis and treatment of various types of cancers associated with abnormal activity of protein kinase A. In particular, the present invention provides genetic and other sequence information, as well as assay systems that will find use in these and related areas.Type: ApplicationFiled: August 23, 2001Publication date: January 30, 2003Applicant: The Government Of USA, Department Of Health And Human ServicesInventors: Constantine Stratakis, Lawrence Kirschner
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Patent number: 5674529Abstract: Multiparticulate controlled release preparations incorporating an alkalinizing potassium salt, preferably potassium bicarbonate, as an active ingredient, which are suitable for forming pharmaceutical dosage forms for oral administration. Such dosage forms are useful for potassium supplementation and for the treatment of degenerative bone or cardiovascular diseases, e.g., osteoporosis and hypertension.Type: GrantFiled: June 6, 1995Date of Patent: October 7, 1997Assignee: Church & Dwight Co., Inc.Inventors: Herman Marder, Lawrence Kirschner, John J. Steinke, Andrew D. Kurtz, Poul Bertelsen, Nils Gjerlov Hansen, Thyge Borup Hjorth
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Patent number: 5509971Abstract: A process for removing coatings from hard surfaces includes blasting the surfaces with a free-flowing particulate blast media entrained in a pressurized fluid, the blast media containing a major amount of relatively soft granular abrasive particles which have a Mohs hardness of less than 4.0 and a minor amount of free-flowing, separate relatively hard granular abrasive particles which have a hardness of greater than 5.0 on the Mohs scale, the granular abrasives having a particle size of from about 10 to about 2000 microns and being devoid of crystalline silica material.Type: GrantFiled: January 27, 1995Date of Patent: April 23, 1996Assignee: Church & Dwight Co., Inc.Inventor: Lawrence Kirschner
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Patent number: 5505749Abstract: A blast media for removing coatings from hard surfaces such as steel includes a major amount of a granular relatively soft abrasive having a Mohs hardness of less than 4 and a minor portion of a granular hard abrasive having a Mohs hardness of greater than 5.Type: GrantFiled: November 8, 1993Date of Patent: April 9, 1996Assignee: Church & Dwight Co., Inc.Inventors: Lawrence Kirschner, Benny S. Yam
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Patent number: 5445805Abstract: A large size, small surface area, granular crystalline potassium bicarbonate product suitable for application as an active ingredient in pharmaceutical oral unit dosage forms useful for the treatment of various degenerative bone and cardiovascular diseases, particularly osteoporosis or hypertension, comprising potassium bicarbonate crystals having a mean particle size of at least 350 microns and a specific B.E.T. surface area less than 0.02 m.sup.2 /gram. A process for preparing such product is further provided, in which a solution of potassium bicarbonate is fed to a slurry of potassium bicarbonate crystals in a crystallizer and the temperatures and concentrations of the potassium bicarbonate in the feed solution and the crystallizer slurry are so regulated, and the residence time and degree of agitation in the crystallizer are so controlled, that the desired large size, small surface area potassium bicarbonate crystals are produced.Type: GrantFiled: May 6, 1993Date of Patent: August 29, 1995Assignee: Church & Dwight Co., Inc.Inventors: William Zuccarello, Andrew D. Kurtz, Lawrence Kirschner, Herman Marder
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Patent number: 5443822Abstract: This invention provides an improved antiperspirant-deodorant cosmetic stick product. An essential aspect of the cosmetic stick product is a content of particulate antiperspirant and alkali metal bicarbonate ingredients, at least one of which has ingredient particle surfaces coated with a hydrophilic organic polymer.Type: GrantFiled: July 12, 1993Date of Patent: August 22, 1995Assignee: Church & Dwight Co., Inc.Inventors: Wendy R. Greczyn, M. Stephen Lajoie, John R. Berschied, Lawrence Kirschner
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Patent number: 5439493Abstract: A blast media for removing coatings from steel comprises a major amount of a granular relatively soft abrasive such as trona, i.e., natural sodium sesquicarbonate, and a minor portion of a granular hard abrasive such as aluminum oxide.Type: GrantFiled: August 3, 1993Date of Patent: August 8, 1995Assignee: Church & Dwight Co., Inc.Inventor: Lawrence Kirschner
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Patent number: 5354553Abstract: This invention provides an improved process for producing an antiperspirant-deodorant cosmetic stick product. An essential aspect of the process improvement is a phased order of ingredient addition and blending of formulation ingredients under controlled temperature conditions. Another essential aspect is the incorporation of particulate antiperspirant and alkali metal bicarbonate ingredients, at least one of which has ingredient particle surfaces coated with a hydrophilic organic polymer.Type: GrantFiled: December 8, 1992Date of Patent: October 11, 1994Assignee: Church & Dwight Co., IncInventors: Wendy R. Greczyn, M. Stephen Lajoie, John R. Berschied, Lawrence Kirschner
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Corrosion-inhibiting cleaning systems for aluminum surfaces, particularly aluminum aircraft surfaces
Patent number: 5232514Abstract: An alkaline blast cleaning system for aluminum surfaces which avoids discoloring or tarnishing of the aluminum surfaces, is comprised of an alkali metal bicarbonate having a particle size of from about 50 to about 1000 and an aqueous solution of sodium silicate, the sodium silicate having an SiO.sub.2 :Na.sub.2 O ratio of from about 2.44 to about 3.22:1 and being present in the aqueous solution in a corrosion inhibiting concentration of from about 100 to about 1000 ppm., the pH of the solution ranging from about 8.1 to about 8.3.Type: GrantFiled: October 10, 1991Date of Patent: August 3, 1993Assignee: Church & Dwight Co., Inc.Inventors: Jack H. Van Sciver, Lawrence Kirschner -
Patent number: 5230185Abstract: A conventional blasting apparatus is modified to provide a separate source of line air to a blast pot through a pressure regulator to provide a greater pressure in the blast pot than is provided to the conveying hose. This differential pressure is maintained by an orifice having a predetermined area situated between the blast pot and the conveying hose. This orifice provides an exit for the blast medium and a relatively small quantity of air from the blast pot to the conveying hose, and ultimately to the nozzle and finally the workpiece. The differential air pressure, typically operating between 1.0 and 15.0 psi with an orifice having an appropriate area, yields acceptable media flow rates in a controlled manner.Type: GrantFiled: November 19, 1991Date of Patent: July 27, 1993Assignee: Church & Dwight Co., Inc.Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
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Patent number: 5160547Abstract: Blasting media for removing coatings from sensitive metal and composite surfaces, and a process useful therewith, wherein the blasting media comprise mixtures of water-soluble crystalline sodium bicarbonate particles having average particle sizes of from 100-500 microns.Type: GrantFiled: May 17, 1991Date of Patent: November 3, 1992Assignee: Church & Dwight Co., Inc.Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
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Patent number: 5112406Abstract: Blasting media for removing coatings from sensitive metal and composite surfaces, and a process useful therewith, wherein the blasting media comprise mixtures of water-soluble crystalline sodium sulfate particles having average particle sizes of from 100 to 250 microns, in admixture with flow/anticaking agents.Type: GrantFiled: December 3, 1991Date of Patent: May 12, 1992Assignee: Church & Dwight Co., Inc.Inventors: Michael S. Lajoie, Lawrence Kirschner
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Patent number: 5083402Abstract: Conventional industrial pressure blasting apparatus is modified to allow a controlled pressure on the blast pot that is greater than the pressure on the line where less aggressive abrasive media and air are mixed for conveying the mixture to the nozzle and then to the workpiece. A media control device, with a fixed but readily variable area, is placed between the blast pot and the media/air mixing line to meter the media flow and maintain a positive pressure differential between the blast pot and the line. Adjusting the pressure differential allows control of the weight ratio of the media-to-air flow to between about 0.05 to 0.25.Type: GrantFiled: April 4, 1991Date of Patent: January 28, 1992Assignee: Church & Dwight Co., Ind.Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
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Patent number: 5081799Abstract: Conventional industrial pressure blasting apparatus is modified to allow a controlled pressure on the blast pot that is greater than the pressure on the line where the media and air are mixed for conveying the mixture to the nozzle and then to the workpiece. A media control device, with a fixed but readily variable area, is placed between the blast pot and the media/air mixing line to meter the media flow and maintain the pressure differential between the blast pot and the line. This allows control of the media flow when low flow rates, below about 10 pounds per minute, are required.Type: GrantFiled: July 12, 1991Date of Patent: January 21, 1992Assignee: Church & Dwight Co., Inc.Inventors: Lawrence Kirschner, Michael S. Lajoie, William E. Spears, Jr.
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Patent number: 4265790Abstract: Dry blended carbonate or phosphate-based laundry detergents are prepared by adding to unhydrated or partially hydrated builder salts, a pH buffering compound and a detergent active compound, together with other formulating agents, coarse, hydrous granular water soluble silicate particles, the silicate particles passing a 10 mesh screen and about 95% of the particles are retained on a 100 mesh screen, according to the disclosed method. Dry blended laundry detergents so formulated are substantially completely free of insoluble product lumps when used in cold wash water in the temperature range of 35.degree.-75.degree. F.Type: GrantFiled: August 9, 1979Date of Patent: May 5, 1981Assignee: Church & Dwight Co., Inc.Inventors: Anthony E. Winston, Francis R. Cala, Stephen P. Lengyel, Lawrence Kirschner, Dragomir Bracilovic