Patents by Inventor Lawrence L. Rudel

Lawrence L. Rudel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for predicting risk of coronary stenosis
    Patent number: 9726683
    Abstract: A computer-based method for determining a prediction of risk and/or an indication of extent of coronary stenosis in a human subject, comprises the steps of: (a) inputting the level of at least one cholesteryl ester measured in a blood sample collected from said subject; and then (b) inputting the age and gender of said subject; and then (c) generating in said computer from said cholesteryl ester level input, said age input and said gender input a prediction of risk and/or an indication of extent of coronary stenosis in said subject. Systems and methods are also described.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: August 8, 2017
    Assignee: Wake Forest University Health Sciences
    Inventors: Lawrence L. Rudel, Chadwick D. Miller, Michael J. Thomas
  • COMPOSITIONS AND METHODS FOR THE TREATMENT AND MANAGEMENT OF STEATOSIS IN HUMAN LIVER
    Publication number: 20160367537
    Abstract: Compositions and methods for the treatment and management of steatosis are disclosed.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 22, 2016
    Inventor: Lawrence L. Rudel
  • SYSTEMS AND APPARATUS FOR INDICATING RISK OF CORONARY STENOSIS
    Publication number: 20160169922
    Abstract: A computer-based method for determining a prediction of risk and/or an indication of extent of coronary stenosis in a human subject, comprises the steps of: (a) inputting the level of at least one cholesteryl ester measured in a blood sample collected from said subject; and then (b) inputting the age and gender of said subject; and then (c) generating in said computer from said cholesteryl ester level input, said age input and said gender input a prediction of risk and/or an indication of extent of coronary stenosis in said subject. Systems and methods are also described.
    Type: Application
    Filed: November 23, 2015
    Publication date: June 16, 2016
    Inventors: Lawrence L. Rudel, Chadwick D. Miller, Michael J. Thomas
  • Methods of measuring amount of cholesteryl ester in a blood sample
    Patent number: 9222948
    Abstract: A method of measuring an amount of at least one cholesteryl ester in a blood sample is carried out by combining a blood sample with a salt and an alcohol to provide a dilute sample; introducing the dilute sample into a mass spectrometer; and then measuring the amount of the at least one cholesteryl ester in the dilute sample by mass spectrometry, to thereby measure the amount of at least one cholesteryl ester in the blood sample, is described.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: December 29, 2015
    Assignee: Wake Forest University Health Sciences
    Inventors: Lawrence L. Rudel, Chadwick D. Miller, Michael J. Thomas
  • SYSTEMS AND APPARATUS FOR INDICATING RISK OF CORONARY STENOSIS
    Publication number: 20140134654
    Abstract: A computer-based method for determining a prediction of risk and/or an indication of extent of coronary stenosis in a human subject, comprises the steps of: (a) inputting the level of at least one cholesteryl ester measured in a blood sample collected from said subject; and then (b) inputting the age and gender of said subject; and then (c) generating in said computer from said cholesteryl ester level input, said age input and said gender input a prediction of risk and/or an indication of extent of coronary stenosis blood sample by mass spectrometry.
    Type: Application
    Filed: May 30, 2012
    Publication date: May 15, 2014
    Applicant: Wake Forest University Health Sciences
    Inventors: Lawrence L. Rudel, Chadwick D. Miller, Michael J. Thomas