Abstract: An endotracheal tube holder has a body which is secured by a pair of non-stretchable, head encircling straps to overlie the patient's mouth and portions of the cheeks. The straps, which are adapted to extend, one above and the other below, the patient's ears, have one-way tightening adjustability by pawl action. The body is integrally molded to incorporate a quick-acting clamp having three integral hinges, one hinge pivotally connecting a pair of jaws of the clamp and the other two hinges supporting the jaws from resilient arms for snap-action between open and closed positions. The clamp is operative to secure or release the endotracheal tube while the straps retain the body in position on the mouth against dislodgment.