Abstract: A medical pouch is disclosed comprising separable inner and outer pouches. The medical pouch may be a collection pouch such as an ostomy pouch. The inner pouch may be replaceable, and be designed for disposal in a water closet. The inner pouch may be of water dispersible or water disintegrateable material, and may be activateable by application of a suitable additive. The inner pouch may be secured in position in the outer pouch by a separable adhesive coupling. The outer pouch may include a refastenable openable portion to facilitate replacement of the inner pouch. The refastenable openable portion may be closed by a zipper. A curved zipper slider may be integrated in the pouch seam.