Abstract: The present invention relates to compositions comprising thyroxine (T4) and triiodothyronine (T3). More specifically, the invention relates to thyroxine (T4) and triiodothyronine (T3) compositions that include a peptide carrier and thyroxine (T4) and triiodothyronine (T3) covalently attached to at least one of the N-terminus, the C-terminus, a side chain of the peptide carrier, and/or interspersed within the peptide chain; methods for protecting and administering thyroxine (T4) and triiodothyronine (T3); and methods for treating thyroid disorders.

Abstract: The invention relates to admixtures of the thyroid hormones and derivatives thereof. These admixtures, particularly L-thyroxine (T4) and liothyronine (T3), produce steady state or near steady state serum levels of T3. When admixed in the appropriate ratio of T4 to T3, blood levels of T3 hormone are maintained at a steady state for an extended period of time independent of the need for control release excipients. The change in the kinetics of T3 absorption is controlled by the addition of T4 to T3.

Abstract: The present invention relates to compositions comprising an active agent. More specifically, the invention relates to active agent compositions that include a peptide carrier and an active agent covalently attached to at least one of the N-terminus, the C-terminus, a side chain of the peptide carrier, and/or interspersed within the peptide chain; methods for protecting and administering active agents; and methods for treating thyroid disorders.