Patents by Inventor Lawrence R. Bernstein

Lawrence R. Bernstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical administration of certain azaspiranes to prevent or treat skin conditions associated with hyperproliferation of skin cells and/or immunologically mediated disorders
    Patent number: 5916885
    Abstract: A locally administrable topical pharmaceutical composition is provided for prevention or treatment of skin conditions associated with hyperproliferation of skin cells and/or an immunologically mediated disorder, e.g., psoriasis, atopical dermatitis, contact dermatitis, seborrhoeic dermatitis, lupus and the like. The composition contains a topical carrier and spirogermanium or a structurally related azaspirane. Also provided are methods for using the novel composition and laminated patches which may be applied to the skin to administer the composition thereto.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: June 29, 1999
    Inventor: Lawrence R. Bernstein
  • Topical administration of azaspiranes to prevent or treat skin conditions associated with hyperproliferation of keratinocytes
    Patent number: 5843936
    Abstract: A locally administrable topical pharmaceutical composition is provided for use in the prevention or treatment of skin conditions associated with hyperproliferation of keratinocytes and/or an immunologically mediated disorders, as psoriasis, atopic dermatitis, contact dermatitis, seborrheic dermatitis or actinic dermatitis. The composition contains a topical carrier and spirogermanium or a structurally related azaspirane.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: December 1, 1998
    Inventor: Lawrence R. Bernstein
  • Methods and compositions to inhibit keratinocyte proliferation
    Patent number: 5747482
    Abstract: Disclosed are methods to inhibit mammalian skin cell proliferation and, in particular, human keratinocyte proliferation by the topical administration of neutral gallium complexes.
    Type: Grant
    Filed: July 30, 1996
    Date of Patent: May 5, 1998
    Inventor: Lawrence R. Bernstein
  • Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
    Patent number: 5574027
    Abstract: Disclosed are pharmaceutical compositions that comprise gallium complexes of 3-hydroxy-4-pyrones. These compositions provide enhanced gallium bioavailability particularly when orally administered as compared to the gallium bioavailability achieved by use of pharmaceutical compositions containing gallium salts. Compositions included in this invention are useful in providing gallium to humans and other mammals for a wide variety of medical and veterinary applications, including the treatment, prevention, or diagnosis of hypercalcemia, certain cancers, certain disorders of calcium homeostasis, and certain bone diseases including osteoporosis, osteopenia, and Paget's disease.
    Type: Grant
    Filed: July 21, 1995
    Date of Patent: November 12, 1996
    Inventor: Lawrence R. Bernstein
  • Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
    Patent number: 5258376
    Abstract: Disclosed are pharmaceutical compositions that comprise gallium complexes of 3-hydroxy-4-pyrones. These compositions provide enhanced gallium bioavailability particularly when orally administered as compared to the gallium bioavailability achieved by use of pharmaceutical compositions containing gallium salts. Compositions included in this invention are useful in providing gallium to humans and other mammals for a wide variety of medical and veterinary applications, including the treatment, prevention, or diagnosis of hypercalcemia, certain cancers, certain disorders of calcium homeostasis, and certain bone diseases including osteoporosis, osteopenia, and Paget's disease.
    Type: Grant
    Filed: October 25, 1991
    Date of Patent: November 2, 1993
    Inventor: Lawrence R. Bernstein