Patents by Inventor Lawrence R. Sharma

Lawrence R. Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to clear meningitis causing agents using antibodies to peptides representing epitopic sites for bacterial and viral meningitis causing agents
    Patent number: 8071102
    Abstract: Novel vaccines include polypeptides that comprise regions corresponding to a chemokine and a hapten. The hapten can be an amino acid sequence corresponding to the Meningitis Related Homologous Antigenic Sequences (MRHAS) of bacterial and viral agents known to cause meningitis. Protective immunity in a host susceptible to meningitis can be induced by inoculating the host with immunogenic amount of such a vaccine.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: December 6, 2011
    Inventors: Diane Van Alstyne, Lawrence R. Sharma
  • Peptides representing epitopic sites for bacterial and viral meningitis causing agents and their CNS carrier and uses thereof
    Patent number: 5556757
    Abstract: Peptides comprising a Meningitis Related Homologous Antigenic Sequence (MRHAS) are provided. The MRHAS is found in meningitis-causing organisms and chemokines involved in cell chemotaxis. The peptides are useful as antigens and vaccines for detection, diagnosis and treatment of meningitis.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 17, 1996
    Assignee: Insight Biotek, Inc.
    Inventors: Diane V. Alstyne, Lawrence R. Sharma
  • Antibodies which bind meningitis related homologous antigenic sequences
    Patent number: 5510264
    Abstract: Monoclonal antibodies capable of binding to a Meningitis Related Homologous Antigenic Sequence (MRHAS) are provided. The MRHAS is found in meningitis-causing organisms and chemokines involved in cell chemotaxis. The monoclonal antibodies are useful for detection and diagnosis of meningitis.
    Type: Grant
    Filed: September 28, 1993
    Date of Patent: April 23, 1996
    Assignee: Insight Biotech Inc.
    Inventors: Diane Van Alstyne, Lawrence R. Sharma