Patents by Inventor Lawrence S. B. Goldstein

Lawrence S. B. Goldstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plus end-directed microtubule motor required for chromosome congression
    Publication number: 20090076248
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP-E modulators using biologically active CENP-E, and kits for screening for CENP-E modulators.
    Type: Application
    Filed: August 22, 2007
    Publication date: March 19, 2009
    Applicant: The Regents of the University of California
    Inventors: Kenneth W. Wood, Roman Sakowicz, Lawrence S.B. Goldstein, Don W. Cleveland
  • Plus end-directed microtubule motor required for chromosome congression
    Patent number: 7276331
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP-E modulators using biologically active CENP-E, and kits for screening for CENP-E modulators.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: October 2, 2007
    Assignee: The Regents of the University of California
    Inventors: Kenneth W. Wood, Roman Sakowicz, Lawrence S. B. Goldstein, Don W. Cleveland
  • Plus end-directed microtubule motor required for chromosome congression
    Patent number: 7009043
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP-E modulators using biologically active CENP-E, and kits for screening for CENP-E modulators.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: March 7, 2006
    Assignee: The Regents of the University of California
    Inventors: Kenneth W. Wood, Roman Sakowicz, Lawrence S. B. Goldstein, Don W. Cleveland
  • Identification and expression of a novel kinesin motor protein
    Patent number: 6815169
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of TL-&ggr;, antibodies to TL-&ggr;, methods of screening for TL-&ggr; modulators using biologically active TL-&ggr;, and kits for screening for TL-&ggr; modulators.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: November 9, 2004
    Assignee: The Regents of the University of California
    Inventors: Roman Sakowicz, Lawrence S. B. Goldstein
  • Kinesin motor modulators derived from the marine sponge Adocia
    Publication number: 20040176625
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Application
    Filed: March 3, 2004
    Publication date: September 9, 2004
    Applicant: The Regents of the University of California
    Inventors: Lawrence S.B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann
  • Kinesin motor modulators derived from the marine sponge Adocia
    Patent number: 6777200
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: August 17, 2004
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann
  • Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
    Patent number: 6764830
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of TL-&ggr;, antibodies to TL-&ggr;, methods of screening for TL-&ggr; modulating using biologically active TL-&ggr;, and kits for screening for TL-&ggr;modulators.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: July 20, 2004
    Assignee: The Regents of the University of California
    Inventors: Roman Sakowicz, Lawrence S. B. Goldstein
  • Identification and expression of a novel kinesin motor protein
    Patent number: 6723840
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of TL-&ggr;, antibodies to TL-&ggr;, methods of screening for TL-&ggr; modulators using biologically active TL-&ggr;, and kits for screening for TL-&ggr; modulators.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: April 20, 2004
    Assignee: The Regents of the University of California
    Inventors: Roman Sakowicz, Lawrence S. B. Goldstein
  • Assays for inhibitors of neuronal transport of Alzheimer's amyloid precursor protein
    Patent number: 6673332
    Abstract: The present invention provides methods and compositions for the treatment of Alzheimer's disease. In particular, the present invention provides methods and compositions suitable to assess, characterize, and identify inhibitors of neuronal transport of Alzheimer's amyloid precursor protein.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: January 6, 2004
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, Adeela Kamal, Gorazd Stokin
  • Plus end-directed microtubule motor required for chromosome congression
    Patent number: 6645748
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP-E modulators using biologically active CENP-E, and kits for screening for CENP-E modulators.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: November 11, 2003
    Assignee: The Regents of the University of California
    Inventors: Kenneth W. Wood, Roman Sakowicz, Lawrence S. B. Goldstein, Don W. Cleveland
  • Kinesin motor modulators derived from the marine sponge adocia
    Publication number: 20030127621
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Application
    Filed: November 27, 2002
    Publication date: July 10, 2003
    Inventors: Lawrence S.B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann
  • Kinesin motor modulators derived from the marine sponge Adocia
    Patent number: 6489134
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: December 3, 2002
    Assignee: The Regents of the University of California
    Inventors: Lawrence S.B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann
  • Kinesin motor modulators derived from the marine sponge Adocia
    Patent number: 6207403
    Abstract: This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: March 27, 2001
    Assignee: The Regents of the University of California
    Inventors: Lawrence S. B. Goldstein, David John Faulkner, Roman Sakowicz, Michael S. Berdelis, Christine L. Blackburn, Cordula Hopmann