Abstract: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

Abstract: A method for codeless development of an application includes registering one or more actions in a registry. Each action is coded in a reusable block of code, each action having an action definition including an action type name, an input parameters map, and an output parameters map. The method further includes performing an action type name look up in the registry for an invoked action with an action service ensuring that a number of arguments included in the action definition matches a number of arguments specified by the action type, passing an input to and receiving a return value from the invoked action, updating the output parameters map included in the definition of the invoked action, and returning the updated output parameters map to an application in development for updating processing variables in the application.

Abstract: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

Abstract: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

Abstract: A method for codeless development of an application includes registering one or more actions in a registry. Each action is coded in a reusable block of code, each action having an action definition including an action type name, an input parameters map, and an output parameters map. The method further includes performing an action type name look up in the registry for an invoked action with an action service ensuring that a number of arguments included in the action definition matches a number of arguments specified by the action type, passing an input to and receiving a return value from the invoked action, updating the output parameters map included in the definition of the invoked action, and returning the updated output parameters map to an application in development for updating processing variables in the application.

Abstract: In one general aspect, a method can include creating an action, the creating including annotating a block of code with metadata, and encapsulating the annotated block of code into a reusable building block of code. The method can further include publishing the action, the publishing including registering the action in a service registry. The method can further include dynamically discovering the action in the service registry by an application during runtime, invoking the action by the application, and executing the action by the application, the executing performing a method specified by the action.

Abstract: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

Abstract: In one general aspect, a method can include creating an action, the creating including annotating a block of code with metadata, and encapsulating the annotated block of code into a reusable building block of code. The method can further include publishing the action, the publishing including registering the action in a service registry. The method can further include dynamically discovering the action in the service registry by an application during runtime, invoking the action by the application, and executing the action by the application, the executing performing a method specified by the action.

Abstract: Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes.

Abstract: Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and uses of these antibodies, are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes.

Abstract: Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes.

Abstract: Methods, systems, and devices for installing barriers in openings of gaps in or between structures such as walls, ceilings, and floors are described herein. At least one barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is preferably operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to create a barrier in the hole or gap.

Abstract: A building element having pressure-sensitive adhesive coating layer having a low initial bond strength, to permit a substrate to be repositioned without destroying the integrity of the adhesive, and a long term bond strength, which occurs after the building element is mechanically fastened to another building element. This allows wood deck components, flooring planks, roofing tiles, and other building material components to be fastened together conveniently while securing a waterproofing and/or sound-deadening effect.

Abstract: The invention provides methods, systems, and devices for installing thermal barriers in openings or gaps in or between structures such as walls, ceilings, and floors. At least one thermal barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to mold a barrier in the hole or gap.

Abstract: Methods and structures involving the use of a double-sided adhesive membrane assembly having one adhesive surface with low initial tackiness to permit a substrate to be re-positionable even if pressed into contact against the adhesive. The method allows wood deck components, flooring planks, roofing tiles, and other building material components to be fastened together conveniently while securing a waterproofing and/or sound-deadening effect.

Abstract: Exemplary methods and assemblies for preventing corrosion of metal connector devices, e.g., zinc-galvanized joist hangers and fasteners, used for assembling outdoor structures such as decks from wood components pretreated with alkaline copper quat (ACQ), ammoniacal copper quat (ACQ-B), copper azole (CA), or mixtures thereof. Membrane barriers separate metal from wood, and seal around fasteners thus minimizing corrosion of the connector devices and fasteners.

Abstract: The invention provides methods, systems, and devices for installing barriers in openings or gaps in or between structures such as walls, ceilings, and floors. At least one barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is preferably operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to create a barrier in the hole or gap.

Abstract: The invention provides methods, systems, and devices for installing barriers in openings or gaps in or between structures such as walls, ceilings, and floors. At least one barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is preferably operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to create a barrier in the hole or gap.

Abstract: The invention provides methods, systems, and devices for installing thermal barriers in openings or gaps in or between structures such as walls, ceilings, and floors. At least one thermal barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to mold a barrier in the hole or gap.

Abstract: The invention provides methods, systems, and devices for installing thermal barriers in openings or gaps in or between structures such as walls, ceilings, and floors. At least one thermal barrier molding bag is positioned in the hole or gap, and a flowable firestop material that is operative to cure or harden, such as a hydratable cementitious slurry, is introduced into the bag to mold a barrier in the hole or gap.