Abstract: Described is a compressed multiple layer pharmaceutical tablet that has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been completed. The width is measured as the greatest horizontal dimension of the tablet at a location halfway between the top and the bottom of the tablet, except that when the horizontal cross-section of the tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of the horizontal cross-section, and measuring the length of a line that is at right angle to the shorter sides. The layers can form a segment or, preferably, more than one segment.

Abstract: A drug-containing pharmaceutical tablet adapted for accurate breaking which has two or more segments with at least one segment containing a drug.

Abstract: A method for providing partial doses of a drug or drugs is disclosed. The method includes breaking of a tablet configured to have an active layer as a first segment and an inactive support layer or substrate as a second segment, or breaking a layered tablet through a first active segment which is deeply or completely scored.

Abstract: The invention provides a novel “separation marking” on a tablet as a means for assisting in the identification of a region on the tablet that is desired to be able to be broken from time to time. Said breaking allows production of smaller dosage forms known herein as tablettes. In a preferred embodiment, the separation mark will be a printed mark that is made on the tablet surface.

Abstract: A method for the treatment of systemic arterial hypertension, which is based on the oral administration to a patient suffering from systemic arterial hypertension either in an amount of chlorthalidone of 2.5-10 mg daily, alone or in novel combination use with another anti-hypertensive.agent.

Abstract: Provided are pharmaceutical dosage forms within structures such as hollow capsules, gelcaps, or sachets, adapted to allow ingestion of a whole dose or a preferably predetermined fraction of said dose when desired.

Abstract: A solid pharmaceutical dosage form having a plurality of adhesively-joined subunits and also having one or more of the following: A. (i) a first inert tablet subunit and (ii) a second active subunit; B. (i) a first tablet subunit with a pharmacologically inactive layer in which said layer has a mass of at least 20 mg and (ii) a second subunit; C. a tablet subunit that is provided with a separation mark; or D. (i) a first tablet subunit and (ii) a second capsule subunit that is adhesively joined to said first tablet subunit.

Abstract: A vehicular traffic control server includes monitoring means tariff, adjusting means in communication with the monitoring means, and notifying means in communication with the tariff adjusting means. The monitoring means is configured to monitor at least one traffic congestion parameter of a roadway having a road tariff. The tariff adjusting means is configured to adjust the road tariff in accordance with the monitored traffic congestion parameter. The notifying means is configured to notify at least one motorist of the adjusted road tariff.

Abstract: A device is provided that responds in real time, as well as in a rhythmic fashion, through amplification and processing of an audio signal. The device also will change in intensity. The electronics work off of three DC power supplies derived from a single AC source. The DC power supplies supply DC sources to the lamp voltage, audio amplifier and darlington network. The circuit takes a line (low) level signal into a capacitively coupled audio amplifier IC. The amplified output is then fed through an isolation transformer into a full-wave bridge rectifier to become a pulsed DC to drive the darlington network. The darlington network, used for voltage gain, drives the bases of the lamp driver transistors which are staggered respectively, through diodes to produce the visual effect. The circuit is not limited to driving lamps of any particular wattage or to the housing of the visual display.