Patents by Inventor Lawrence Stern

Lawrence Stern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148826
    Abstract: Nucleic acid molecules that include a nucleotide sequence encoding a chimeric antigen receptor (CAR) and a nucleotide sequence encoding a protease sensitive scFv, wherein the chimeric antigen receptor comprises: an scFv targeting a tumor antigen, a spacer, a transmembrane domain, a co-stimulatory domain, and a CD3 ? signaling domain; and the protease-sensitive scFv and the scFv target the same tumor antigen are described.
    Type: Application
    Filed: June 5, 2023
    Publication date: May 9, 2024
    Inventors: Xiuli Wang, Stephen J. Forman, Lawrence Stern, Christine E. Brown, Joseph Cohen
  • Publication number: 20230372483
    Abstract: Chimeric antigen receptor molecules that include a variant IL-13. The variant IL-13 are more selective for IL13R?2 than IL13R?1 by virtue of weaker binding to IL13R?1. The chimeric antigen receptors can be used to treat IL13R?2 expressing cancers.
    Type: Application
    Filed: January 19, 2021
    Publication date: November 23, 2023
    Inventors: Christine E. Brown, Lawrence Stern, Xin Yang, K. Christopher Garcia, Ignacio Moraga Gonzalez
  • Patent number: 11701405
    Abstract: Nucleic acid molecules that include a nucleotide sequence encoding a chimeric antigen receptor (CAR) and a nucleotide sequence encoding a protease sensitive scFv, wherein the chimeric antigen receptor comprises: an scFv targeting a tumor antigen, a spacer, a transmembrane domain, a co-stimulatory domain, and a CD3? signaling domain; and the protease-sensitive scFv and the scFv target the same tumor antigen are described.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: July 18, 2023
    Assignee: City of Hope
    Inventors: Xiuli Wang, Stephen J. Forman, Lawrence Stern, Christine E. Brown, Joseph Cohen
  • Publication number: 20210046155
    Abstract: Nucleic acid molecules that include a nucleotide sequence encoding a chimeric antigen receptor (CAR) and a nucleotide sequence encoding a protease sensitive scFv, wherein the chimeric antigen receptor comprises: an scFv targeting a tumor antigen, a spacer, a transmembrane domain, a co-stimulatory domain, and a CD3 ? signaling domain; and the protease-sensitive scFv and the scFv target the same tumor antigen are described.
    Type: Application
    Filed: January 25, 2019
    Publication date: February 18, 2021
    Inventors: Xiuli Wang, Stephen J. Forman, Lawrence Stern, Christine E. Brown, Joseph Cohen
  • Patent number: 8999011
    Abstract: This invention relates to low sulfur marine/bunker fuel compositions and methods of making same. Contrary to conventional marine/bunker fuel compositions/methods, the inventive lower sulfur compositions/methods focus on use of mostly uncracked components, such as (cat feed) hydrotreated gasoils, and/or can also have reduced contents of residual components.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: April 7, 2015
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: David Lawrence Stern, Salvatore R. Di Mauro, Aldo Roccaro, Paul William Bessonette
  • Patent number: 8957266
    Abstract: Provided are processes for making one or more unsaturated oligomeric acids and one or more saturated hydrocarbons. In one form, a process for making one or more saturated hydrocarbons includes oligomerizing one or more unsaturated carboxylic acids having from 4 to 38 carbon atoms in the presence of a molecular sieve catalyst to form one or more unsaturated oligomeric acids including less than 90% by weight of cyclic oligomers, and hydrogenating the one or more unsaturated oligomeric acids via contact with hydrogen in the presence of a hydrogenation catalyst to form one or more saturated hydrocarbons. The oligomerizing of unsaturated fatty acids is from renewable biological sources to form dimer acids. The one or more saturated hydrocarbons are useful as lubricant base oils.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: February 17, 2015
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Kun Wang, Margaret May-Som Wu, David Lawrence Stern
  • Patent number: 8920541
    Abstract: A method is provided for replacing at least a portion of the organic linker content of a zeolitic imidazolate framework composition. The method comprises exchanging the organic linker with another organic linker. Also provided is a new material, designated as EMM-19, and a method of using EMM-19 to adsorb gases, such as carbon dioxide.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 30, 2014
    Assignee: ExxonMobile Research and Engineering Company
    Inventors: Zheng Ni, Mobae Afeworki, Simon Christopher Weston, John Zengel, David Lawrence Stern
  • Patent number: 8907102
    Abstract: A method is provided for forming a zeolitic imidazolate framework composition using at least one reactant that is relatively insoluble in the reaction medium. Also provided herein is a material made according to the method, designated as EMM-19, and a method of using EMM-19 to adsorb gases, such as carbon dioxide.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 9, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Simon Christopher Weston, Mobae Afeworki, Zheng Ni, John Zengel, David Lawrence Stern
  • Patent number: 8772562
    Abstract: A process for converting feedstock triglycerides to lube basestocks. The process has the steps of (a) metathesizing the feedstock triglycerides with ethylene in the presence of a metathesis catalyst to form alpha olefins and medium-chain triglycerides and (b) hydroisomerizing the medium-chain triglycerides in the presence of a hydroisomerization catalyst and hydrogen to form methyl-branched triglycerides. The alpha olefins may be oligomerized in the presence of an oligomerization catalyst to form poly(alpha olefins).
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: July 8, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Kun Wang, Margaret May-Som Wu, Alan Anthony Galuska, David Lawrence Stern
  • Patent number: 8636969
    Abstract: A method is provided for forming a zeolitic imidazolate framework composition using at least one reactant that is relatively insoluble in the reaction medium. Also provided herein is a material made according to the method, designated either as EMM-19 or as EMM-19*, and a method of using same to adsorb and/or separate gases, such as carbon dioxide.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 28, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Simon Christopher Weston, Mobae Afeworki, Zheng Ni, John Zengel, David Lawrence Stern
  • Publication number: 20130340323
    Abstract: This invention relates to low sulfur marine/bunker fuel compositions and methods of making same. Contrary to conventional marine/bunker fuel compositions/methods, the inventive lower sulfur compositions/methods focus on use of mostly uncracked components, such as (cat feed) hydrotreated gasoils, and/or can also have reduced contents of residual components.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 26, 2013
    Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: David Lawrence Stern, Salvatore R. Di Mauro, Aldo Roccaro, Paul William Bessonette
  • Publication number: 20130259792
    Abstract: A method is provided for forming a zeolitic imidazolate framework composition using at least one reactant that is relatively insoluble in the reaction medium. Also provided herein is a material made according to the method, designated either as EMM-19 or as EMM-19*, and a method of using same to adsorb and/or separate gases, such as carbon dioxide.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 3, 2013
    Applicant: ExxonMobil Research & Engineering Company
    Inventors: Simon Christopher Weston, Mobae Afeworki, Zheng Ni, John Zengel, David Lawrence Stern
  • Publication number: 20130259783
    Abstract: A method is provided for replacing at least a portion of the organic linker content of a zeolitic imidazolate framework composition. The method comprises exchanging the organic linker with another organic linker. Also provided is a new material, designated as EMM-19, and a method of using EMM-19 to adsorb gases, such as carbon dioxide.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 3, 2013
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Zheng Ni, Mobae Afeworki, Simon Christopher Weston, John Zengel, David Lawrence Stern
  • Patent number: 8347242
    Abstract: A method, computer program product, and apparatus for processing a wiring diagram is provided. Information associated with a number of components in the wiring diagram is identified. A scaling factor between a first format for the wiring diagram and a second format used by a software application configured to use wiring diagrams in the second format is identified. The scaling factor is applied to the information identified as being associated with the number of components in the wiring diagram to form processed information.
    Type: Grant
    Filed: January 5, 2010
    Date of Patent: January 1, 2013
    Assignee: The Boeing Company
    Inventors: Molly Louise Boose, David Brayton Shema, Lawrence Sterne Baum, Joseph Charles Hrin
  • Publication number: 20120115762
    Abstract: A process for converting feedstock triglycerides to lube basestocks. The process has the steps of (a) metathesizing the feedstock triglycerides with ethylene in the presence of a metathesis catalyst to form alpha olefins and medium-chain triglycerides and (b) hydroisomerizing the medium-chain triglycerides in the presence of a hydroisomerization catalyst and hydrogen to form methyl-branched triglycerides. The alpha olefins may be oligomerized in the presence of an oligomerization catalyst to form poly(alpha olefins).
    Type: Application
    Filed: November 10, 2010
    Publication date: May 10, 2012
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Kun Wang, Margaret May-Som Wu, Alan Anthony Galuska, David Lawrence Stern
  • Publication number: 20110167401
    Abstract: A method, computer program product, and apparatus for processing a wiring diagram is provided. Information associated with a number of components in the wiring diagram is identified. A scaling factor between a first format for the wiring diagram and a second format used by a software application configured to use wiring diagrams in the second format is identified. The scaling factor is applied to the information identified as being associated with the number of components in the wiring diagram to form processed information.
    Type: Application
    Filed: January 5, 2010
    Publication date: July 7, 2011
    Applicant: THE BOEING COMPANY
    Inventors: Molly Louise Boose, David Brayton Shema, Lawrence Sterne Baum, Joseph Charles Hrin
  • Patent number: 7868215
    Abstract: A process for producing cumene is provided which comprises the step of contacting benzene and propylene under at least partial liquid phase alkylating conditions with a particulate molecular sieve alkylation catalyst, wherein the particles of said alkylation catalyst have a surface to volume ratio of about 80 to less than 200 inch?1.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: January 11, 2011
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Ajit B. Dandekar, Michael Hryniszak, David Lawrence Stern
  • Publication number: 20100234654
    Abstract: Provided are processes for making one or more unsaturated oligomeric acids and one or more saturated hydrocarbons. In one form, a process for making one or more saturated hydrocarbons includes oligomerizing one or more unsaturated carboxylic acids having from 4 to 38 carbon atoms in the presence of a molecular sieve catalyst to form one or more unsaturated oligomeric acids including less than 90% by weight of cyclic oligomers, and hydrogenating the one or more unsaturated oligomeric acids via contact with hydrogen in the presence of a hydrogenation catalyst to form one or more saturated hydrocarbons. The oligomerizing of unsaturated fatty acids is from renewable biological sources to form dimer acids. The one or more saturated hydrocarbons are useful as lubricant base oils.
    Type: Application
    Filed: March 4, 2010
    Publication date: September 16, 2010
    Inventors: Kun Wang, Margaret May-Som Wu, David Lawrence Stern
  • Publication number: 20100056835
    Abstract: A process for producing cumene is provided which comprises the step of contacting benzene and propylene under at least partial liquid phase alkylating conditions with a particulate molecular sieve alkylation catalyst, wherein the particles of said alkylation catalyst have a surface to volume ratio of about 80 to less than 200 inch?1.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 4, 2010
    Inventors: Ajit B. Dandekar, Michael Hryniszak, David Lawrence Stern
  • Patent number: 7638668
    Abstract: A process for producing cumene is provided which comprises the step of contacting benzene and propylene under at least partial liquid phase alkylating conditions with a particulate molecular sieve alkylation catalyst, wherein the particles of said alkylation catalyst have a surface to volume ratio of about 80 to less than 200 inch?1.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: December 29, 2009
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Ajit B. Dandekar, Michael Hryniszak, David Lawrence Stern