Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for searching chemical structures. One of the methods includes receiving a fingerprint map for each chemical structure of a collection of chemical structures, generating an inverted index for the collection of chemical structures, receiving a request to search the inverted index for matching chemical structures, obtaining a query fingerprint for the query structure, computing a minimum number of bits and a maximum number of bits that must be present in respective fingerprints of candidate structures in the collection of chemical structures in order for a candidate structure to be considered a match for the query structure, and traversing the inverted index to identify candidate structures having fingerprints with a number of bits in between the minimum number of bits and the maximum number of bits.

Abstract: An exemplary method includes transmitting, by a software application subsystem, a request to an encryption services subsystem to route a message generated by an originating software application to a recipient software application through a message broker subsystem, acquiring, by the software application subsystem, data representative of a current encryption configuration of the message broker subsystem from the encryption services subsystem in response to the request, and determining, by the software application subsystem, during a run time of the originating software application whether to encrypt the message before the message is transmitted to the message broker subsystem for routing to the recipient software application, the determination based at least in part on the current encryption configuration of the message broker subsystem. Corresponding methods and systems are also disclosed.

Abstract: An exemplary method includes transmitting, by a software application subsystem, a request to an encryption services subsystem to route a message generated by an originating software application to a recipient software application through a message broker subsystem, acquiring, by the software application subsystem, data representative of a current encryption configuration of the message broker subsystem from the encryption services subsystem in response to the request, and determining, by the software application subsystem, during a run time of the originating software application whether to encrypt the message before the message is transmitted to the message broker subsystem for routing to the recipient software application, the determination based at least in part on the current encryption configuration of the message broker subsystem. Corresponding methods and systems are also disclosed.

Abstract: A novel system and method is provided for displaying files over a local area network or over the Internet. It is appropriate for displaying either hierarchical information or comparative information either within a company or government entity or within vertical markets. The method includes the steps of defining headings for either non-comparative information or comparative information within any company or government entity or within any vertical market, listing either hierarchical information or the products or services of vendors in a vertical market, including vendors that do not have a Web presence, allowing vendors to enter the information defined by the headings, allowing vendors to enter descriptions differentiating products or services in their market, allowing clients to research products or services, and providing a means of soliciting products or services not listed.

Abstract: A ground implanted support system includes a plurality of conical base members having irregular configurations in transverse cross section which are inserted in preformed complementary holes formed by a tool which is uniformly forced into the ground either manually or by controllable force producing means and thereafter each of the implanted base members receives a bolt, a plug, a post, or the like in a precast opening in the top of each base member. In a preferred form of the invention, the base members are precast from concrete and the base members are not inserted completely in the ground which reduces corrosion of the part being supported by the base members.