Patents by Inventor Lawrence Tumey

Lawrence Tumey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles
    Publication number: 20080076926
    Abstract: A process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles, which can be useful for the preparation of protein kinase inhibitors, is provided.
    Type: Application
    Filed: September 25, 2007
    Publication date: March 27, 2008
    Inventors: Diane Boschelli, Lawrence Tumey, Biqi Wu
  • Substituted 3-cyanopyridines as protein kinase inhibitors
    Publication number: 20070287708
    Abstract: The present teachings provide compounds of formula I and their pharmaceutically acceptable salts, hydrates, and esters, wherein R1, R2, and X are as defined herein. The present teachings also provide methods of making the compounds of formula I, and methods of treating autoimmune and inflammatory diseases by administering a therapeutically effective amount of a compound or compounds of formula I to a mammal including a human.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 13, 2007
    Inventors: Derek Cole, Diane Boschelli, Yanong Wang, Magda Asselin, Diane Joseph-McCarthy, Amarnauth Prashad, Allan Wissner, Russell Dushin, Biqi Wu, Lawrence Tumey, Chuan Niu, Joan Chen
  • Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors
    Publication number: 20070082880
    Abstract: Disclosed are compounds of Formula I: wherein R1, R2, R3, R4, and X, are defined hereinbefore in the specification, which can be useful in the treatment of autoimmune and inflammatory diseases, and processes for producing said compounds.
    Type: Application
    Filed: September 27, 2006
    Publication date: April 12, 2007
    Inventors: Diane Boschelli, Derek Cole, Magda Asselin, Ana Barrios Sosa, Biqi Wu, Lawrence Tumey
  • Benzimidazole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof
    Publication number: 20060106081
    Abstract: The invention relates to benzimidazole acetic acid compounds which function as antagonists of the Chemoattractant Receptor-homologous molecule expressed on T-Helper type 2 cells (CRTH2) receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
    Type: Application
    Filed: September 21, 2005
    Publication date: May 18, 2006
    Inventors: Youssef Bennani, Lawrence Tumey, Elizabeth Gleason, Michael Robarge
  • Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof
    Publication number: 20060100425
    Abstract: The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.
    Type: Application
    Filed: September 21, 2005
    Publication date: May 11, 2006
    Inventors: Youssef Bennani, Lawrence Tumey, Elizabeth Gleason, Michael Robarge
  • Substituted azepine derivatives as serotonin receptor modulators
    Publication number: 20060003990
    Abstract: The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are hexahydroazepinoindole and octahydroazepinoindole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).
    Type: Application
    Filed: June 29, 2005
    Publication date: January 5, 2006
    Inventors: Youssef Bennani, Bayard Huck, Michael Robarge, David Bom, Norbert Varga, Lawrence Tumey