Patents by Inventor Lawrence W. Anderson

Lawrence W. Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imaging of drug accumulation as a guide to antitumor therapy
    Patent number: 7175830
    Abstract: The use of radio-labeled antitumor drugs in the treatment of solid tumors by the method of administering a radio-labeled anticancer drug to a patient and imaging at least a part of the patient using Positron Emission Tomography imaging is described. The method can be used to monitor delivery of antitumor drugs to tumors, to predict the effectiveness of therapy with a particular antitumor drug or combination of antitumor drugs, to assess the effectiveness of modulators of cellular accumulation, to individualize therapy and to evaluate the effectiveness of antitumor drugs with respect to particular cancers. Particularly preferred drugs are labeled taxanes, e.g., 11C-paclitaxel and 11C-docetaxel, labeled anthracyclines, e.g., 11C-doxorubicin and 11C-epirubicin, and other radiolabeled drugs, e.g. 11C-topotecan, 11C-SN-38, and 11C-imatinib. The invention further describes antitumor drugs labeled with the radioactive label 11C and methods of preparing radio-labeled drugs.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: February 13, 2007
    Assignee: The United States of America as represented by the Secretary of Health and Human Services
    Inventors: Jerry M. Collins, Raymond W. Klecker, Jr., Lawrence W. Anderson
  • Imaging of drug accumulation as a guide to antitumor therapy
    Publication number: 20030198594
    Abstract: The use of radio-labeled antitumor drugs in the treatment of solid tumors by the method of administering a radio-labeled anticancer drug to a patient and imaging at least a part of the patient using Positron Emission Tomography imaging is described. The method can be used to monitor delivery of antitumor drugs to tumors, to predict the effectiveness of therapy with a particular antitumor drug or combination of antitumor drugs, to assess the effectiveness of modulators of cellular accumulation, to individualize therapy and to evaluate the effectiveness of antitumor drugs with respect to particular cancers. Particularly preferred drugs are labeled taxanes, e.g., 11C-paclitaxel and 11C-docetaxel, labeled anthracyclines, e.g., 11C-doxorubicin and 11C-epirubicin, and other radiolabeled drugs, e.g. 11C-topotecan, 11C-SN-38, and 11C-imatinib. The invention further describes antitumor drugs labeled with the radioactive label 11C and methods of preparing radio-labeled drugs.
    Type: Application
    Filed: December 16, 2002
    Publication date: October 23, 2003
    Inventors: Jerry M. Collins, Raymond W. Klecker, Lawrence W. Anderson
  • Train vehicle protection apparatus including signal block occupancy determination
    Patent number: 3958781
    Abstract: There is disclosed a train vehicle protection apparatus including the determination of train vehicle occupancy of a track circuit signal block, wherein a frequency tone speed code signal is provided to the signal block for controlling the train vehicle speed and a vital and fail-safe determination of train vehicle occupancy of the signal block is provided.
    Type: Grant
    Filed: January 29, 1975
    Date of Patent: May 25, 1976
    Assignee: Westinghouse Electric Corporation
    Inventors: David H. Woods, Lawrence W. Anderson