Patents by Inventor Lawrence Y. Fang

Lawrence Y. Fang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds to treat alzheimer's disease
    Publication number: 20090074746
    Abstract: The present invention is substituted amines of formula (X) useful in treating Alzheimer's disease and other similar diseases.
    Type: Application
    Filed: September 24, 2004
    Publication date: March 19, 2009
    Inventors: Lawrence Y. Fang, Roy Hom, Varghese John, Michel Maillard
  • Methods to Treat Alzheimer's Disease
    Publication number: 20080058336
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases.
    Type: Application
    Filed: October 10, 2006
    Publication date: March 6, 2008
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • Compounds to treat Alzheimer's disease
    Patent number: 7214715
    Abstract: The present invention is substituted amines of formula (X) and of the formula (X?) useful in treating Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: May 8, 2007
    Assignees: Pharmacia & Upjohn, Elan Pharmaceuticals
    Inventors: James P. Beck, Lawrence Y. Fang, John N. Freskos, Andrea Gailunas, Roy Hom, Barbara Jagodzinska, Varghese John, Michel Maillard, Shon R. Pulley, Ruth E. TenBrink
  • Methods to treat alzheimer's disease
    Patent number: 7119085
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: October 10, 2006
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • Compounds to treat Alzheimer's disease
    Patent number: 7034182
    Abstract: The present invention is substituted amines of formula (XV) useful in treating Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: April 25, 2006
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Lawrence Y. Fang, Varghese John
  • Compounds to treat Alzheimer's disease
    Patent number: 7030239
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: April 18, 2006
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • Compounds to treat Alzheimer's disease
    Publication number: 20040214846
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) 1
    Type: Application
    Filed: May 18, 2004
    Publication date: October 28, 2004
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
    Patent number: 6767918
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: July 27, 2004
    Assignees: Athena Neurosciences, Inc., Eli Lilly & Company
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • Compounds to treat Alzheimer's disease
    Patent number: 6737420
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII): useful in treating Alzheimer's disease and other similar diseases.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: May 18, 2004
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • N-(aryl/heteroarylacety) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
    Patent number: 6642261
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: November 4, 2003
    Assignees: Athena Neurosciences, Inc., Eli Lilly & Company
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20030191119
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 9, 2002
    Publication date: October 9, 2003
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • Compounds to treat alzheimer's disease
    Publication number: 20030096864
    Abstract: The present invention is substituted amines of formula (X) 1
    Type: Application
    Filed: June 29, 2001
    Publication date: May 22, 2003
    Inventors: Lawrence Y. Fang, Roy Hom, Varghese John, Michel Maillaird
  • N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20020137743
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: October 31, 2001
    Publication date: September 26, 2002
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • Compounds to treat alzheimer's disease
    Publication number: 20020128255
    Abstract: The present invention is substituted amines of formula (X) 1
    Type: Application
    Filed: June 29, 2001
    Publication date: September 12, 2002
    Inventors: James P. Beck, Lawrence Y. Fang, John N. Freskos, Andrea Gailunas, Roy Hom, Barbara Jagodzinska, Varghese John, Michel Maillard, Shon R. Pulley, Ruth E. TenBrink
  • Compounds to treat alzheimer's disease
    Publication number: 20020022623
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) 1
    Type: Application
    Filed: March 23, 2001
    Publication date: February 21, 2002
    Inventors: Roy Hom, Shumeye Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • Methods to treat alzheimer's disease
    Publication number: 20020019403
    Abstract: The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) 1
    Type: Application
    Filed: March 23, 2001
    Publication date: February 14, 2002
    Inventors: Roy Hom, Shumeye S. Mamo, Jay Tung, Andrea Gailunas, Varghese John, Lawrence Y. Fang
  • Compounds to treat alzheimer's disease
    Publication number: 20020016320
    Abstract: The present invention is substituted amines of formula (XV) 1
    Type: Application
    Filed: June 29, 2001
    Publication date: February 7, 2002
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: Lawrence Y. Fang, Varghese John
  • N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
    Patent number: 6333351
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: December 25, 2001
    Assignees: Athena Neurosciences, Inc., Eli Lilly & Company
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • N(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
    Patent number: 6313152
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: November 6, 2001
    Assignees: Athena Neurosciences, Inc., Eli Lilly and Company
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia
  • N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use
    Patent number: 6117901
    Abstract: Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: September 12, 2000
    Assignees: Athena Neurosciences, Inc., Eli Lilly & Company
    Inventors: Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Thomas E. Mabry, Lee H. Latimer, Varghese John, Lawrence Y. Fang, James E. Audia