Patents by Inventor Lawrence Yu
Lawrence Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11478195Abstract: A multi-sensor system may include a catheter that has lumen, is flexible, is made of a polymer, and has a circular cross section that has an outer diameter of no more than 0.5 cm; and one or more sensors that sense multiple characteristics of material flowing within the lumen, including at least two of the following: flow rate, pressure, and composition of the material. A multi-sensor system may include a catheter that has lumen, is flexible, is made of a polymer, and has a circular cross section that has an outer diameter of no more than 0.5 cm; and one or more sensors that sense multiple characteristics of material flowing within the lumen, including at least two of the following: flow rate, pressure, and composition of the material.Type: GrantFiled: January 13, 2016Date of Patent: October 25, 2022Assignee: University of Southern CaliforniaInventors: Brian J. Kim, Lawrence Yu, Ellis Meng, Alexander Baldwin
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Patent number: 11428657Abstract: A sensor for measuring electrochemical impedance includes a primary circuit that includes a primary electrically conducting coil and a secondary circuit that includes a secondary electrically conducting coil. The primary electrically conducting coil is inductively coupled to the secondary circuit. During operation, the secondary electrically conductive couple has contact electrodes that contact a medium for which the impedance is to be measured. An alternating current source energizes the primary electrically conducting coil during impedance measurements.Type: GrantFiled: June 5, 2017Date of Patent: August 30, 2022Assignee: University of Southern CaliforniaInventors: Ellis F. Meng, Lawrence Yu
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Publication number: 20190227014Abstract: A sensor for measuring electrochemical impedance includes a primary circuit that includes a primary electrically conducting coil and a secondary circuit that includes a secondary electrically conducting coil. The primary electrically conducting coil is inductively coupled to the secondary circuit. During operation, the secondary electrically conductive couple has contact electrodes that contact a medium for which the impedance is to be measured. An alternating current source energizes the primary electrically conducting coil during impedance measurements.Type: ApplicationFiled: June 5, 2017Publication date: July 25, 2019Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Ellis F. MENG, Lawrence YU
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Patent number: 10030033Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.Type: GrantFiled: August 3, 2016Date of Patent: July 24, 2018Assignee: GILEAD SCIENCES, INC.Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondappally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
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Publication number: 20170217952Abstract: The invention provides a crystalline form of the compound of formula (Ia), methods for making the crystalline form of the compound of formula (Ia), and therapeutic methods for the use of the crystalline form of the compound of formula (Ia).Type: ApplicationFiled: January 24, 2017Publication date: August 3, 2017Inventors: Chiajen Lai, Lok Him Lawrence Yu, Richard Hung Chiu Yu
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Publication number: 20170210756Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.Type: ApplicationFiled: August 3, 2016Publication date: July 27, 2017Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Christopher Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
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Patent number: 9440991Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.Type: GrantFiled: December 18, 2014Date of Patent: September 13, 2016Assignee: Gilead Sciences, Inc.Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
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Publication number: 20150175626Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.Type: ApplicationFiled: December 18, 2014Publication date: June 25, 2015Applicant: GILEAD SCIENCES, INC.Inventors: Amy Cagulada, Johann Chan, Lina Chan, Denise A. Colby, Kapil Kumar Karki, Darryl Kato, Katie Ann Keaton, Sudha Kondapally, Chris Levins, Adam Littke, Ruben Martinez, Dominika Pcion, Troy Reynolds, Bruce Ross, Michael Sangi, Adam J. Schrier, Pamela Seng, Dustin Siegel, Nathan Shapiro, Donald Tang, James G. Taylor, Jonathan Tripp, Andrew W. Waltman, Lawrence Yu
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Patent number: 8895020Abstract: Single chain trimer (SCT) molecules are disclosed, comprising an MHC antigen peptide sequence, a ?2-microglobulin sequence and a full-length MHC class I heavy chain sequence, joined by linker sequences. Further described are nucleic acids encoding single chain trimers. Methods for expansion of antigen-specific T cell populations using single chain trimer molecules are also disclosed. In some configurations, these methods comprise co-culturing, in a first stage, CD8+ T cells from a donor with antigen presenting cells comprising an MHC antigen peptide, and co-culturing, in a second stage, the CD8+ T cells with cells comprising an SCT which has an MHC antigen peptide sequence identical to the sequence of the antigen peptide in the first stage. The methods can provide 10,000-100,000 fold expansion of antigen-specific CD8+ T cells within about 28 days after establishing culture, and can yield over 1 billion antigen-specific CD8+ T cells expanded from an individual donor.Type: GrantFiled: April 4, 2006Date of Patent: November 25, 2014Assignee: Washington UniversityInventors: Ted Hansen, Yik Yeung Lawrence Yu
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Publication number: 20080219947Abstract: Single chain trimer (SCT) molecules are disclosed, comprising an MHC antigen peptide sequence, a ?2-microglobulin sequence and a full-length MHC class I heavy chain sequence, joined by linker sequences. Further described are nucleic acids encoding single chain trimers. Methods for expansion of antigen-specific T cell populations using single chain trimer molecules are also disclosed. In some configurations, these methods comprise co-culturing, in a first stage, CD8+ T cells from a donor with antigen presenting cells comprising an MHC antigen peptide, and co-culturing, in a second stage, the CD8+ T cells with cells comprising an SCT which has an MHC antigen peptide sequence identical to the sequence of the antigen peptide in the first stage. The methods can provide 10,000-100,000 fold expansion of antigen-specific CD8+ T cells within about 28 days after establishing culture, and can yield over 1 billion antigen-specific CD8+ T cells expanded from an individual donor.Type: ApplicationFiled: April 4, 2006Publication date: September 11, 2008Inventors: Gerald P. Linette, Ted Hansen, Michelle Becker-Hapak, Yik Yeung Lawrence Yu
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Publication number: 20030211782Abstract: A filtered RJ11 connector module that is adaptable for mounting on Home Phone Networking Alliance (HPNA) network interface card useful for home networking applications and other communication protocols involves the integration of filter module into the connector module itself. The filter module comprises an isolation transformer, common mode choke, filter components, high voltage capacitor and surge protection device that may be configured to customize any network interface card. Mounting of at least two light indicators on a printed circuit board is another embodiment of the invention and therefore, also an integral part of a filtered RJ11 connector module. The housing consists of at least one plug-receiving opening for receiving connector plugs that are electrically connected to a transmission medium.Type: ApplicationFiled: May 7, 2002Publication date: November 13, 2003Applicant: Mr. Joseph Lorenzo De GuzmanInventors: Lawrence Yu Esparaz, Danny Alvaro Villaron, Joseph Lorenzo De Guzman
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Patent number: 5339898Abstract: The invention involves combining a plurality of vertical wells, each having a power conditioning unit located on the surface and an electrode in electrical contact with the reservoir, with a horizontal well extending through the reservoir in spaced relation to the vertical wells. The liner and tubing of the horizontal well function as the common return means for the circuit. Low frequency current is supplied to flow between the vertical and horizontal wells at adequate levels so as to cause heating in the near-wellbore regions of all the wells. Oil is produced, at the same time as electrical heating, at enhanced rates as a result.Type: GrantFiled: July 13, 1993Date of Patent: August 23, 1994Assignee: Texaco Canada Petroleum, Inc.Inventors: C. Lawrence Yu, Bruce C. W. McGee, Frederick S. Chute, Fred E. Vermeulen